Regulation and controlling the motility properties of Pseudomonas aeruginosa
Chronic infections caused by Pseudomonas aeruginosa have been a major concern as their spread and mortality continue to be on the rise. These infections are majorly attributed to biofilm formation via sequential steps where motility plays an essential role in initial attachment of bacterial cells onto biotic and abiotic surfaces, thereby contributing to multi-drug resistance among pathogens. Therefore, attenuating motility properties can be considered as highly potential for controlling P. aeruginosa biofilm formation. This strategy has employed the use of various natural and chemically synthesized compounds. The present review article explained the importance and regulation of different types of motilities properties. Furthermore, it also covered several important alternative approaches using anti-motility agents which could be helpful for controlling P. aeruginosa biofilm-associated infections. Further studies are required for in-depth understandings about the mechanisms of motilities controlling of these molecules at molecular levels.
2020
2021-01-12 06:36:05
1033
Biofilm, Motility, Attenuation, Antibiofilm drugs, Pseudomonas aeruginosa
r6
Fazlurrahman
Khan
70
Dung Thuy Nguyen
Pham
70
Sandra
Oloketuyi
70
Young-Mog
Kim
70
COBISS_ID
3
46628867
DOI
15
10.1007/s00253-019-10201-w
NUK URN
18
URN:SI:UNG:REP:O9Z3AFMB
Khan2020_Article_RegulationAndControllingTheMot_(1).pdf
5063842
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2021-01-12 06:36:07