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1.
Role of interfaces in nanostructured CoFe [sub] 2 O [sub] 4 films
Anna-Karin Axelsson, Frederic Aguesse, Neil McN. Alford, Matjaž Valant, 2012, published scientific conference contribution

Found in: osebi
Keywords: magnetizem, spineli, tanki filmi
Published: 15.10.2013; Views: 2304; Downloads: 22
URL Fulltext (0,00 KB)

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Performance of the Cherenkov Telescope Array at energies above 10 TeV
Anna Barnacka, Darko Veberič, 2013, published scientific conference contribution

Found in: osebi
Keywords: astronomija žarkov gama, Observatorij Cherenkov Telescope Array, teleskopi, občutljivost
Published: 15.10.2013; Views: 1632; Downloads: 6
URL Fulltext (0,00 KB)

6.
Narrative discourse in anomic aphasia
Andrea Marini, Anna Cantagallo, Sara Andreetta, 2012, original scientific article

Abstract: Anomic aphasia is a disturbance affecting lexical retrieval. Nonetheless, persons with this disorder may also experience difficulties in the construction of coherent narratives. Whether this symptom is a sign of a macrolinguistic difficulty per se or reflects the lexical disorder is still an open debate. In order to analyze the effect of the lexical impairment on macrolinguistic processing, we compared the narrative skills of a group of ten participants with chronic anomic aphasia with those of ten healthy control individuals matched for age and educational level. The anomic participants produced narratives with lowered speech rate, reduced mean length of utterance, fewer grammatically well-formed sentences, more semantic paraphasias. The macrolinguistic analysis showed that they also produced more errors of cohesion and global coherence and fewer lexical information units. Interestingly, their levels of thematic selection were normal. A bivariate correlational analysis showed a strong correlation between the production of errors of cohesion and production of complete sentences, and between production of errors of global coherence and lexical information units. These correlations showed that aspects related to lexical retrieval may affect macrolinguistic processing during the construction of a narrative. Indeed, it is suggested that lexical deficits lead to two main consequences: First, patients with anomia frequently interrupt the utterances they are producing and this reduces the levels of sentence completeness and the overall degree of cohesion across the utterances; Second, they use strategies to cope with the lexical impairment and produce a quantity of lexical fillers and repetitions that, clustered in utterances, reduce the levels of global coherence.
Found in: osebi
Keywords: aphasia, neurolinguistics, speech disorders, discourse analysis
Published: 07.03.2016; Views: 1250; Downloads: 0
.pdf Fulltext (391,66 KB)

7.
Narrative discourse in anomic aphasia
Sara Andreetta, Anna Cantagallo, Andrea Marini, 2012, original scientific article

Found in: osebi
Keywords: afazija, govorne motnje, nevropsihologija, analiza diskurza, aphasia, neurolinguistics, speech disorders, discourse analysis
Published: 09.05.2017; Views: 995; Downloads: 4
URL Fulltext (0,00 KB)

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The VPS4 component of the ESCRT machinery plays an essential role in HPV infectious entry and capsid disassembly
Lawrence Banks, Colin Crump, Anna Gozdzicka-Jozefiak, Martina Bergant, David Pim, Paola Massimi, Justyna Broniarczyk, 2017, original scientific article

Abstract: Human Papillomavirus (HPV) infection involves multiple steps, from cell attachment, through endocytic trafficking towards the trans-Golgi network, and, ultimately, the entry into the nucleus during mitosis. An essential viral protein in infectious entry is the minor capsid protein L2, which engages different components of the endocytic sorting machinery during this process. The ESCRT machinery is one such component that seems to play an important role in the early stages of infection. Here we have analysed the role of specific ESCRT components in HPV infection, and we find an essential role for VPS4. Loss of VPS4 blocks infection with multiple PV types, suggesting an evolutionarily conserved critical step in infectious entry. Intriguingly, both L1 and L2 can interact with VPS4, and appear to be in complex with VPS4 during the early stages of virus infection. By using cell lines stably expressing a dominant-negative mutant form of VPS4, we also show that loss of VPS4 ATPase activity results in a marked delay in capsid uncoating, resulting in a defect in the endocytic transport of incoming PsVs. These results demonstrate that the ESCRT machinery, and in particular VPS4, plays a critical role in the early stages of PV infection.
Found in: osebi
Keywords: HPV, ESCRT machinery, infection
Published: 08.05.2017; Views: 1161; Downloads: 86
.pdf Fulltext (1,10 MB)

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