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Методичні рекомендації до лабораторного практикуму з курсу «Радикальні реакції в клітині»
Олена Душенко, Ганна Степаненко, Вікторія Одарюк, Ольга Кущ, 2017, drugo učno gradivo

Opis: Посібник містить методичні вказівки для виконання лабораторних робіт з курсу «Радикальні реакції у клітині». Призначено для аудиторної та самостійної роботи студентів.
Ključne besede: радикальні реакції, методичні рекомендації
Objavljeno: 30.07.2019; Ogledov: 204; Prenosov: 0
.pdf Polno besedilo (1,62 MB)

On a class of D-division hypernear-ring
Irina Cristea, Sanja Jančić-Rašović, objavljeni povzetek znanstvenega prispevka na konferenci

Ključne besede: hypernear-ring, distributivity, near-ring
Objavljeno: 25.07.2019; Ogledov: 176; Prenosov: 0
.pdf Polno besedilo (7,38 MB)

Multiendomorphisms as a tool to construct new hyperrings
Sanja Jančić-Rašović, Irina Cristea, 2015, objavljeni povzetek znanstvenega prispevka na konferenci

Ključne besede: hyperring, multiendomorphism
Objavljeno: 25.07.2019; Ogledov: 230; Prenosov: 0
.pdf Polno besedilo (2,79 MB)

Manjšinska literatura in literatura obmejnega območja EDUKA2
ana toroš, druga izvedena dela

Opis: Vodenje projektne delovne skupine EDUKA2 DS 3.1.5. - skupne učne enote o manjšinski literaturi ter literaturi obmejnega območja
Ključne besede: EDUKA2, Trst, Gorica, Videm, Istra, literatura, didaktika
Objavljeno: 23.07.2019; Ogledov: 224; Prenosov: 0
.pdf Polno besedilo (991,88 KB)

Breathomics and its Application for Disease Diagnosis: A Review of Analytical Techniques and Approaches
Enzo A Palombo, Konstantinos A Kouremenos, Ding Y Oh, Iain R White, David J Beale, Avinash V Karpe, Oliver A H Jones, 2018, samostojni znanstveni sestavek ali poglavje v monografski publikaciji

Opis: The application of metabolomics to an ever-greater variety of sample types is a key focus of systems biology research. Recently, there has been a strong focus on applying these approaches toward the rapid analysis of metabolites found in non-invasively acquired samples, such as exhaled breath (also known as ‘breathomics’). The sampling process involved in collecting exhaled breath is nonintrusive and comparatively low-cost. It uses a series of globally approved methods and provides researchers with easy access to the metabolites secreted by the human body. Owing to its accuracy and rapid nature, metabolomic analysis of breath is a rapidly growing field that has proven effective in detecting and diagnosing the early stages of numerous diseases and infections. This review discusses the various collection and analysis methods currently applied in breathomics research. Some of the salient research completed in this field to date is also assessed and discussed in order to provide a basis for possible future scientific directions.
Ključne besede: Metabolomics, breath research, VOCs, breathomics
Objavljeno: 22.07.2019; Ogledov: 201; Prenosov: 0
.pdf Polno besedilo (25,96 MB)

Capturing and Storing Exhaled Breath for Offline Analysis
Stephen J Fowler, Iain R White, 2019, samostojni znanstveni sestavek ali poglavje v monografski publikaciji

Opis: In this chapter we will summarize and discuss methods for the capture and storage of exhaled breath, prior to offline (and indirect online) analysis. We will detail and compare methods currently in use, including their applications, key strengths, and limitations. In synthesizing the best features of each technique, we will propose an ideal standardized breath sampling solution, and give a personal vision on the next steps to be taken in this exciting area of breath research.
Ključne besede: Breath analysis, Breath sampling, Offline analysis, Thermal desorption, Gas chromatography-mass spectrometry
Objavljeno: 22.07.2019; Ogledov: 155; Prenosov: 0
.pdf Polno besedilo (36,24 MB)

The effect of serum withdrawal on the protein profile of quiescent human dermal fibroblasts in primary cell culture.
Quaglino Daniela, Tiozzo Roberta, Paolinelli Devincenzi Chiara, Annovi Giulia, Boraldi Federica, 2008, izvirni znanstveni članek

Opis: The effect of serum deprivation on proliferating cells is well known, in contrast its role on primary cell cultures, at confluence, has not been deeply investigated. Therefore, in order to explore the response of quiescent cells to serum deprivation, ubiquitous mesenchymal cells, as normal human dermal fibroblasts, were grown, for 48 h after confluence, in the presence or absence of 10% FBS. Fibroblast behaviour (i.e. cell morphology, cell viability, ROS production and elastin synthesis) was evaluated morphologically and biochemically. Moreover, the protein profile was investigated by 2-DE and differentially expressed proteins were identified by MS. Serum withdrawal caused cell shrinkage but did not significantly modify the total cell number. ROS production, as evaluated by the dihydroethidium (DH2) probe, was increased after serum deprivation, whereas elastin synthesis, measured by a colorimetric method, was markedly reduced in the absence of serum. By proteome analysis, 41 proteins appeared to significantly change their expression, the great majority of protein changes were related to the cytoskeleton, the stress response and the glycolytic pathway. Data indicate that human dermal fibroblasts in primary cell culture can adapt themselves to environmental changes, without significantly altering cell viability, at least after a few days of treatment, even though serum withdrawal represents a stress condition capable to increase ROS production, to influence cell metabolism and to interfere with cell behaviour, favouring the expression of several age-related features.
Ključne besede: Dermal fibroblasts / Primary cell culture / ROS production / Serum withdrawal
Objavljeno: 22.07.2019; Ogledov: 213; Prenosov: 0
.pdf Polno besedilo (462,68 KB)

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