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Naslov:WATER-POLYPEPTIDE INTERACTION IN CLASSICAL MODELS OF HELIX-COIL TRANSITION
Avtorji:Yeritsyan, Knarik (Avtor)
Badasyan, Artem (Mentor) Več o mentorju... Novo okno
Datoteke:.pdf Knarik_Yeritsyan.pdf (1,70 MB)
 
Jezik:Angleški jezik
Vrsta gradiva:Diplomsko delo/naloga (mb11)
Tipologija:2.11 - Diplomsko delo
Organizacija:FN - Fakulteta za naravoslovje
Opis:Zimm-Bragg model is the simplest to describe the conformational transitions in biopolymers and is regularly used for preocessing the experimental data. We review the model and its Hamiltonian definition with the goal to introduce the interaction with water into the picture. We show how modified ZB model with the account of water-polypeptide interactions allows to describe both cold denaturation and helix-coil transition and derive such the formula explicitly. The obtained theoretical expression for the helicity degree contains two independent parameters that can be fitted with the experimental data to determine the parameters of cold denaturation and helix-coil transition from a single fit and for a single set of experimental data.
Ključne besede:Zimm-Bragg model, conformational transitions in biopolymers, cold denaturation
Leto izida:2016
Izvor:Nova Gorica
COBISS_ID:4512763  Povezava se odpre v novem oknu
URN:URN:SI:UNG:REP:G9A5Q0OH
Število ogledov:947
Število prenosov:45
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
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