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Title:Physics behind the Conformational Transitions in Biopolymers. Demystification of DNA melting and Protein Folding
Authors:Badasyan, Artem V. (Author)
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Language:English
Work type:Not categorized (r6)
Tipology:3.14 - Invited Lecture at Foreign University
Organization:UNG - University of Nova Gorica
Abstract:Biophysics is the area of research, devoted to the studies of physical problems related to living systems. Animal cell is the smallest unit of an organism and mainly contains water solutions of structurally inhomogeneous polymers of biological origin: polypeptides (proteins) and polynucleotides (DNA, RNA). Statistical physics of macromolecules allows to describe the conformations of both synthetic and bio-polymers and constitutes the basis of Biophysics. During the talk I will report on the biophysical problems I have solved with numerical simulations (Langevin-based Molecular Dynamics of Go-like protein folding model and Monte Carlo with Wang-Landau sampling) and analytical studies of spin models (formula evaluation by hand, enforced with computer algebra systems). The direct connections with the theory of phase transitions, algebra of non-commutative operators and decorated spin models will be elucidated.
Keywords:Biophysics, protein folding, helix-coil transition, spin models
Year of performance:2016
Place of performance:Institut za fiziku, Bijenička 46, 10000 Zagreb, Hrvaska
COBISS_ID:4603899 Link is opened in a new window
URN:URN:SI:UNG:REP:MXBVMU6Y
Views:1407
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