Repozitorij Univerze v Novi Gorici

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Naslov:SIGNALING STUDIES IN THE EMERGING KIWIFRUIT PATHOGEN Pseudomonas syringae pv. actinidiae
Avtorji:Javvadi, Sree Gowrinadh (Avtor)
Venturi, Vittorio (Mentor) Več o mentorju... Novo okno
Datoteke:.pdf Sree_Gowrinadh_Javvadi.pdf (4,41 MB)
 
Jezik:Angleški jezik
Vrsta gradiva:Doktorsko delo/naloga (mb31)
Tipologija:2.08 - Doktorska disertacija
Organizacija:FPŠ - Fakulteta za podiplomski študij
Opis:In the past two decades emerging and re-emerging plant pathogens have caused new threats to the production of several economically important crops, one among them is P. syringae pv. actinidiae (PSA) which causes canker or leaf spot on kiwifruit plants. PSA enters plant through wounds and remains dormant in cortex tissue of the branches, and spreads in the tissue to cause severe symptoms from winter to early spring. The disease can be visualized by brown discoloration of buds, dark brown angular spots surrounded by yellow haloes on leaves, cankers with white to reddish (oxydation) exudate on twigs and trunks, fruit collapse, wilting and eventually plant mortality. Current control methods have their own significance in disease control, however there is considerable lack of clear understanding of PSA pathogenicity. Virulence of plant pathogens often relies on the synchronized/coordinated expression of pathogenicity factors via quorum sensing (QS). Therefore, investigations on QS in PSA may lead to develop novel disease control strategies and reliable methods to curb the disease. It is currently unknown whether PSA produces a QS signal molecule thus the aim of this thesis is to investigate whether PSA possesses a QS system. As genome mining did not reveal the presence of any currently known QS system, this study initially by metabolomics was aimed at identifying potentially low molecular weight secondary metabolite QS molecules produced by PSA. Azelaic acid was discovered to be produced by PSA, this is the first report of azelaic acid production by bacteria. The characterization and possible role of azelaic acid in QS is presented. Since azelaic acid is ubiquitous in nature, in addition to determining its biological role, the catabolism of azelaic acid in bacteria using the efficient degrader Pseudomonas nitroreducens DSM 9128 was also studied.
Ključne besede:Quorum sensing, Azelaic acid, Metabolomics, Catabolism
Leto izida:2017
Izvor:Nova Gorica
COBISS_ID:4974587 Povezava se odpre v novem oknu
URN:URN:SI:UNG:REP:ZKM02EHD
Število ogledov:2027
Število prenosov:117
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
Področja:Gradivo ni uvrščeno v področja.
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