Repozitorij Univerze v Novi Gorici

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Naslov:Real-time multi-marker measurement of organic compounds in human breath: Towards fingerprinting breath
Avtorji:White, Iain R (Avtor)
Willis, Kerry A (Avtor)
Whyte, Christopher (Avtor)
Cordell, Rebecca (Avtor)
Blake, Robert S (Avtor)
Wardlaw, Andrew J (Avtor)
Datoteke:Gradivo nima datotek. Gradivo je morda fizično dosegljivo v knjižnici fakultete, zalogo lahko preverite v COBISS-u. Povezava se odpre v novem oknu
Jezik:Angleški jezik
Vrsta gradiva:Delo ni kategorizirano (r6)
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:UNG - Univerza v Novi Gorici
Opis:The prospects for exploiting proton transfer reaction-time of flight-mass spectrometry (PTR-ToF-MS) in medical diagnostics are illustrated through a series of case studies. Measurements of acetone levels in the breath of 68 healthy people are presented along with a longitudinal study of a single person over a period of 1 month. The median acetone concentration across the population was 484 ppbV with a geometric standard deviation (GSD) of 1.6, whilst the average GSD during the single subject longtitudinal study was 1.5. An additional case study is presented which highlights the potential of PTR-ToF-MS in pharmacokinetic studies, based upon the analysis of online breath samples of a person following the consumption of ethanol. PTR-ToF-MS comes into its own when information across a wide mass range is required, particularly when such information must be gathered in a short time during a breathing cycle. To illustrate this property, multicomponent breath analysis in a small study of cystic fibrosis patients is detailed, which provides tentative evidence that online PTR-ToF-MS analysis of tidal breath can distinguish between active infection and non-infected patients.
Ključne besede:Volatile Organic Compounds, breath, proton transfer reaction mass spectrometry, Cystic Fibrosis
Leto izida:2013
Št. strani:11
Številčenje:7, 1
COBISS_ID:5423867 Povezava se odpre v novem oknu
URN:URN:SI:UNG:REP:WRX9CNKR
DOI:10.1088/1752-7155/7/1/017112 Povezava se odpre v novem oknu
Število ogledov:687
Število prenosov:0
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
Področja:Gradivo ni uvrščeno v področja.
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Skupna ocena:(0 glasov)
Vaša ocena:Ocenjevanje je dovoljeno samo prijavljenim uporabnikom.

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