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Naslov:Fibroblast involvement in soft connective tissue calcification
Avtorji:ID Pasquali Ronchetti, Ivonne, Università di Modena e Reggio Emilia (Avtor)
ID Boraldi, Federica, Università di Modena e Reggio Emilia (Avtor)
ID Annovi, Giulia, Università di Modena e Reggio Emilia (Avtor)
ID Cianciulli, Paolo, S Eugenio Hospital, Rome (Avtor)
ID Quaglino, Daniela, Università di Modena e Reggio Emilia (Avtor)
Datoteke: Gradivo nima datotek, ki so prostodostopne za javnost. Gradivo je morda fizično dosegljivo v knjižnici fakultete, zalogo lahko preverite v COBISS-u. Povezava se odpre v novem oknu
Jezik:Angleški jezik
Vrsta gradiva:Delo ni kategorizirano
Tipologija:1.02 - Pregledni znanstveni članek
Organizacija:UNG - Univerza v Novi Gorici
Opis:Soft connective tissue calcification is not a passive process, but the consequence of metabolic changes of local mesenchymal cells that, depending on both genetic and environmental factors, alter the balance between pro- and anti-calcifying pathways. While the role of smooth muscle cells and pericytes in ectopic calcifications has been widely investigated, the involvement of fibroblasts is still elusive. Fibroblasts isolated from the dermis of pseudoxanthoma elasticum (PXE) patients and of patients exhibiting PXE-like clinical and histopathological findings offer an attractive model to investigate the mechanisms leading to the precipitation of mineral deposits within elastic fibers and to explore the influence of the genetic background and of the extracellular environment on fibroblast-associated calcifications, thus improving the knowledge on the role of mesenchymal cells on pathologic mineralization.
Ključne besede:fibroblasts, PXE, PXE-likedisorders, elastin, extracellularmatrix, ectopiccalcification, mesenchymal stromalcells
Leto izida:2013
Št. strani:1-16
Številčenje:4
PID:20.500.12556/RUNG-4699-a015d0fb-c66f-874e-40c0-aa8b4ad3fbe8 Novo okno
COBISS.SI-ID:5442043 Novo okno
NUK URN:URN:SI:UNG:REP:NR53OB9M
Datum objave v RUNG:23.08.2019
Število ogledov:4266
Število prenosov:0
Metapodatki:XML DC-XML DC-RDF
:
PASQUALI RONCHETTI, Ivonne, BORALDI, Federica, ANNOVI, Giulia, CIANCIULLI, Paolo in QUAGLINO, Daniela, 2013, Fibroblast involvement in soft connective tissue calcification. Frontiers in genetics [na spletu]. 2013. Vol. 4, p. 1–16. [Dostopano 13 april 2025]. Pridobljeno s: https://repozitorij.ung.si/IzpisGradiva.php?lang=slv&id=4699
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Gradivo je del revije

Naslov:Frontiers in genetics
Leto izida:2013

Licence

Licenca:CC BY-NC-ND 4.0, Creative Commons Priznanje avtorstva-Nekomercialno-Brez predelav 4.0 Mednarodna
Povezava:http://creativecommons.org/licenses/by-nc-nd/4.0/deed.sl
Opis:Najbolj omejujoča licenca Creative Commons. Uporabniki lahko prenesejo in delijo delo v nekomercialne namene in ga ne smejo uporabiti za nobene druge namene.
Začetek licenciranja:22.08.2019

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