20.500.12556/RUNG-2515
WATER-POLYPEPTIDE INTERACTION IN CLASSICAL MODELS OF HELIX-COIL TRANSITION
Zimm-Bragg model is the simplest to describe the conformational transitions in biopolymers and is regularly used for preocessing the experimental data. We review the model and its Hamiltonian definition with the goal to introduce the interaction with water into the picture. We show how modified ZB model with the account of water-polypeptide interactions allows to describe both cold denaturation and helix-coil transition and derive such the formula explicitly. The obtained theoretical expression for the helicity degree contains two independent parameters that can be fitted with the experimental data to determine the parameters of cold denaturation and helix-coil transition from a single fit and for a single set of experimental data.
Zimm-Bragg model
conformational transitions in biopolymers
cold denaturation
true
true
false
Angleški jezik
Ni določen
Diplomsko delo/naloga
2016-07-19 15:00:23
2016-09-28 16:41:26
2023-06-09 03:17:27
0000-00-00 00:00:00
2016
0
Nova Gorica
0
0000-00-00
NiDoloceno
NiDoloceno
NiDoloceno
0000-00-00
0000-00-00
0000-00-00
4512763
URN:SI:UNG:REP:G9A5Q0OH
Knarik_Yeritsyan.pdf
Knarik_Yeritsyan.pdf
1
A467D4551EAF7FA698AB28FB2743BD4D
35e46498ba86a86e0708046675875c7969918fd111edf07cc3b2f8b4e3b85f7c
1543290e-05ce-11ee-9c48-5ef991fed68f
https://repozitorij.ung.si/Dokument.php?lang=slv&id=4323
Fakulteta za naravoslovje
0
0
0