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Strategies of biofilm inhibition and virulence attenuation of food borne pathogen-Escherichia coli O157:H7
Sandra Oloketuyi, Fazlurrahman Khan, 2017, review article

Abstract: Enterohemorrhagic Escherichia coli (E. coli) O157:H7, a gram-negative bacteria identified as a foodborne pathogen causing severe disease is of great concern worldwide. The pathogenicity of E. coli O157:H7 is due to the presence of some virulence factors and its ability to form biofilm which resist antimicrobial compounds, withstand harsh environmental condition and protects from the host immune responses. Formation of biofilm is a multistep process such as adhesion, cellular aggregation and productions of extracellular matrix in which colonies are embedded. There are high numbers of research in the discovery of natural and synthetic compounds which can attenuate the E. coli O157:H7 biofilm formation as well as suppress virulence-related genes. The present review article focuses on the steps involved in E. coli O157:H7 biofilm formation, factors associated with virulence and attenuation.
Found in: ključnih besedah
Keywords: Escherichia coli, pathogen, virulence
Published: 14.01.2021; Views: 575; Downloads: 0
.pdf Fulltext (886,73 KB)

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Molecules involved in motility regulation in Escherichia coli cells: a review
Fazlurrahman Khan, Nazia Tabassum, Dung :Pham, Sandra Oloketuyi, Young-Mog Kim, 2020, original scientific article

Abstract: The initial colonization of the host organism by commensal, probiotic, and pathogenic Escherichia coli strains is an important step in the development of infections and biofilms. Sensing and colonization of host cell surfaces are governed by flagellar and fimbriae/pili appendages, respectively. Biofilm formation confers great advantages on pathogenic E. coli cells such as protection against the host immune system, antimicrobial agents, and several environmental stress factors. The transition from planktonic to sessile physiological states involves several signaling cascades and factors responsible for the regulation of flagellar motility in E. coli cells. These regulatory factors have thus become important targets to control pathogenicity. Hence, attenuation of flagellar motility is considered a potential therapy against pathogenic E. coli. The present review describes signaling pathways and proteins involved in direct or indirect regulation of flagellar motility. Furthermore, application strategies for antimotility natural or synthetic compounds are discussed also.
Found in: ključnih besedah
Keywords: Biofilm formation, Escherichia coli, inhibition, motility, pathogenesis
Published: 14.01.2021; Views: 822; Downloads: 0
.pdf Fulltext (2,42 MB)

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Crystal structure of CNG mimicking NaK mutant, NaK-ETPP, Cs+ complex
Matteo De March, L. M. R. Napolitano, S. Onesti, 2015, complete scientific database or corpus

Found in: ključnih besedah
Summary of found: ...crystal structures, Escherichia coli, Bacillus cereus ATCC 14579...
Keywords: crystal structures, Escherichia coli, Bacillus cereus ATCC 14579
Published: 16.03.2021; Views: 435; Downloads: 2
URL Fulltext (0,00 KB)

9.
Crystal structure of CNG mimicking NaK-ETPP mutant cocrystallized with Methylammonium
Matteo De March, L. M. R. Napolitano, S. Onesti, 2015, complete scientific database or corpus

Found in: ključnih besedah
Summary of found: ...structures, transport protein, Bacillus cereus ATCC 14579, Escherichia coli...
Keywords: crystal structures, transport protein, Bacillus cereus ATCC 14579, Escherichia coli
Published: 16.03.2021; Views: 455; Downloads: 2
URL Fulltext (0,00 KB)

10.
The experimental X-ray structure of the new diheme cytochrome type c from Shewanella baltica OS155 sb-DHC
Matteo De March, G. Di Rocco, S. Geremia, 2012, complete scientific database or corpus

Found in: ključnih besedah
Summary of found: ...crystal structures, electron transport, Shewanella baltica OS155, Escherichia coli...
Keywords: crystal structures, electron transport, Shewanella baltica OS155, Escherichia coli
Published: 16.03.2021; Views: 440; Downloads: 2
URL Fulltext (0,00 KB)

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