11. Generation and applications of extreme-ultraviolet vorticesCarlos Hernández-García, Jorge Vieira, Jose T. Mendonça, Laura Rego, Julio San Román, Luis Plaja, Primož Rebernik Ribič, David Gauthier, Antonio Picón, 2017, izvirni znanstveni članek Ključne besede: XUV/X-ray vortices, orbital angular momentum of photons, high-harmonic generation, free-electron lasers, plasma physics Objavljeno v RUNG: 13.01.2020; Ogledov: 3209; Prenosov: 14 Povezava na celotno besedilo |
12. TD/GC–MS analysis of volatile markers emitted from mono- and co-cultures of Enterobacter cloacae and Pseudomonas aeruginosa in artificial sputumIain R. White, Oluwasola Lawal, Hugo Knobel, Weda Hans, Tamara M E Nijsen, Royston Goodacre, Stephen J Fowler, Waqar M Ahmed, Antonio Artigas, Jonathan Barnard-Smith, Lieuwe D Bos, Marta Camprubi, Luis Coelho, Paul Dark, Alan Davie, Emili Diaz, Gemma Goma, Timothy Felton, Jan H Leopold, Pouline M P van Oort, Pedro Póvoa, Craig Portsmouth, 2018, izvirni znanstveni članek Opis: Introduction: Infections such as ventilator-associated pneumonia (VAP) can be caused by one or more pathogens. Current methods for identifying these pathogenic microbes often require invasive sampling, and can be time consuming, due to the requirement for prolonged cultural enrichment along with selective and differential plating steps. This results in delays in diagnosis which in such critically ill patients can have potentially life-threatening consequences. Therefore, a non-invasive and timely diagnostic method is required. Detection of microbial volatile organic compounds (VOCs) in exhaled breath is proposed as an alternative method for identifying these pathogens and may distinguish between mono- and poly-microbial infections. Objectives: To investigate volatile metabolites that discriminate between bacterial mono- and co-cultures. Methods: VAP-associated pathogens Enterobacter cloacae and Pseudomonas aeruginosa were cultured individually and together in artificial sputum medium for 24 h and their headspace was analysed for potential discriminatory VOCs by thermal desorption gas chromatography–mass spectrometry. Results: Of the 70 VOCs putatively identified, 23 were found to significantly increase during bacterial culture (i.e. likely to be released during metabolism) and 13 decreased (i.e. likely consumed during metabolism). The other VOCs showed no transformation (similar concentrations observed as in the medium). Bacteria-specific VOCs including 2-methyl-1-propanol, 2-phenylethanol, and 3-methyl-1-butanol were observed in the headspace of axenic cultures of E. cloacae, and methyl 2-ethylhexanoate in the headspace of P. aeruginosa cultures which is novel to this investigation. Previously reported VOCs 1-undecene and pyrrole were also detected. The metabolites 2-methylbutyl acetate and methyl 2-methylbutyrate, which are reported to exhibit antimicrobial activity, were elevated in co-culture only. Conclusion: The observed VOCs were able to differentiate axenic and co-cultures. Validation of these markers in exhaled breath specimens could prove useful for timely pathogen identification and infection type diagnosis. Ključne besede: Bacteria, Enterobacter cloacae, Gas Chromatography-Mass Spectrometry, Infection, Pseudomonas aeruginosa, Volatile organic compounds Objavljeno v RUNG: 18.07.2019; Ogledov: 4503; Prenosov: 114 Celotno besedilo (1,29 MB) |
13. Bacterial inclusion bodies are industrially exploitable amyloids.Ario De Marco, Neus Ferrer-Miralles, Elena Garcia-Fruitos, Anna Mitraki, Spela Peternel, Ursula Rinas, Mauricio Trujillo-Roldan, Norma Valdez-Cruz, Esther Vazquez, Antonio Villaverde, 2019, pregledni znanstveni članek Ključne besede: inclusion bodies, soluble aggregates, functional proteins Objavljeno v RUNG: 03.01.2019; Ogledov: 3597; Prenosov: 0 Gradivo ima več datotek! Več... |
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16. Giant magneto–electric coupling in 100 nm thick Co capped by ZnO nanorodsGiovanni Vinai, Barbara Ressel, Piero Torelli, Federico Loi, Benoit Gobaut, Regina Ciancio, Barbara Casarin, Antonio Caretta, Luca Capasso, Fulvio Parmigiani, Francesco Cugini, Massimo Solzi, Marco Malvestuto, Roberta Ciprian, 2018, izvirni znanstveni članek Ključne besede: ZnO nanorods, Cobalt, X-rays absorption near edge spectroscopy Objavljeno v RUNG: 07.02.2018; Ogledov: 3926; Prenosov: 0 Gradivo ima več datotek! Več... |
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18. New strategy for magnetic gas sensingRoberta Ciprian, Piero Torelli, Angelo Giglia, B Gobaut, Barbara Ressel, Janez Štupar, Matija Stupar, Antonio Caretta, Giovanni De Ninno, Tommaso Pincelli, Barbara Casarin, Ganesh Adhikari, G Sberviglieri, C Baratto, Marco Malvestuto, 2016, izvirni znanstveni članek Ključne besede: hybrid nanostructures, sensor, absorption spectroscopy Objavljeno v RUNG: 05.02.2018; Ogledov: 4034; Prenosov: 0 Gradivo ima več datotek! Več... |
19. Phenolic profile and effect of regular consumption of Brazilian red wines on in vivo antioxidant activityUrška Vrhovšek, Fulvio Mattivi, E. F. Gris, Eduardo Antonio Ferreira, Danilo Wilhelm Filho, R. C. Pedrosa, Marilde T. Bordigon-Luiz, 2013, izvirni znanstveni članek Ključne besede: vinska trta, vino, antioksidacija, fenolne spojine Objavljeno v RUNG: 09.05.2017; Ogledov: 5032; Prenosov: 39 Povezava na celotno besedilo |
20. Cardiac stem cell aging and heart failureDaniela Cesselli, Aneta Aleksova, Elisa Mazzega, Angela Caragnano, Antonio Paolo Beltrami, 2017, pregledni znanstveni članek Opis: A side effect of the medical improvements of the last centuries is the progressive aging of the world population, which is estimated to reach the impressive number of 2 billion people with more than 65 years by 2050. As a consequence, age-related diseases, such as heart failure, will affect more and more patients in the next years. To understand the biological bases of these diseases will be a crucial task in order to find better treatments, and possibly slow age-related morbidity and mortality.
Cardiac stem cells have been at the center of a heated debate and their potential involvement in cardiac homeostasis has been questioned. In this review, we summarize evidence obtained by independent groups, on different animal models and humans, that strongly support the important role played by immature, cardiac resident cells in the cardioprotection against heart failure. Ključne besede: Aging, Heart failure, Cardiomyocyte turnover, Stem cells, Cell senescence, cKit, Sca1, PDGFRα, Cardiospheres Objavljeno v RUNG: 28.03.2017; Ogledov: 4517; Prenosov: 0 Gradivo ima več datotek! Več... |