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1.
Variability in sediment particle size, mineralogy, and Fe mode of occurrence across dust-source inland drainage basins : the case of the lower Drâa Valley, Morocco
Adolfo Gonzalez-Romero, Cristina González-Flórez, Agnesh Panta, Jesús Yus-Díez, Cristina Reche, Patricia Córdoba, Natalia Moreno, Andrés Alastuey, Konrad Kandler, Martina Klose, 2023, izvirni znanstveni članek

Opis: The effects of desert dust upon climate and ecosystems depend strongly on its particle size and size-resolved mineralogical composition. However, there is very limited quantitative knowledge on the particle size and composition of the parent sediments along with their variability within dust-source regions, particularly in dust emission hotspots. The lower Drâa Valley, an inland drainage basin and dust hotspot region located in the Moroccan Sahara, was chosen for a comprehensive analysis of sediment particle size and mineralogy. Different sediment type samples (n= 42) were collected, including paleo-sediments, paved surfaces, crusts, and dunes, and analysed for particle-size distribution (minimally and fully dispersed samples) and mineralogy. Furthermore, Fe sequential wet extraction was carried out to characterise the modes of occurrence of Fe, including Fe in Fe (oxyhydr)oxides, mainly from goethite and hematite, which are key to dust radiative effects; the poorly crystalline pool of Fe (readily exchangeable ionic Fe and Fe in nano-Fe oxides), relevant to dust impacts upon ocean biogeochemistry; and structural Fe. Results yield a conceptual model where both particle size and mineralogy are segregated by transport and deposition of sediments during runoff of water across the basin and by the precipitation of salts, which causes a sedimentary fractionation. The proportion of coarser particles enriched in quartz is higher in the highlands, while that of finer particles rich in clay, carbonates, and Fe oxides is higher in the lowland dust emission hotspots. There, when water ponds and evaporates, secondary carbonates and salts precipitate, and the clays are enriched in readily exchangeable ionic Fe, due to sorption of dissolved Fe by illite. The results differ from currently available mineralogical atlases and highlight the need for observationally constrained global high-resolution mineralogical data for mineral-speciated dust modelling. The dataset obtained represents an important resource for future evaluation of surface mineralogy retrievals from spaceborne spectroscopy.
Ključne besede: mineral dust, aerosols, geology
Objavljeno v RUNG: 12.01.2024; Ogledov: 432; Prenosov: 3
.pdf Celotno besedilo (7,63 MB)
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2.
Tumour virus research
2021

Objavljeno v RUNG: 07.12.2023; Ogledov: 434; Prenosov: 2
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3.
Insights into the size-resolved dust emission from field measurements in the Moroccan Sahara
Cristina González-Flórez, Martina Klose, Andrés Alastuey, Sylvain Dupont, Jerónimo Escribano, Vicken Etyemezian, Adolfo Gonzalez-Romero, Yue Huang, Konrad Kandler, Jesús Yus-Díez, 2023, izvirni znanstveni članek

Opis: Atmospheric mineral dust consists of tiny mineral particles that are emitted by wind erosion from arid regions. Its particle size distribution (PSD) affects its impact on the Earth's system. Nowadays, there is an incomplete understanding of the emitted dust PSD and a lot of debate about its variability. Here, we try to address these issues based on the measurements performed during a wind erosion and dust emission field campaign in the Moroccan Sahara within the framework of FRAGMENT project.
Ključne besede: aerosol particles, mineral dust, emission processes, climate
Objavljeno v RUNG: 23.10.2023; Ogledov: 770; Prenosov: 5
.pdf Celotno besedilo (23,38 MB)
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Contribution of APOBEC proteins 3A and 3B to the oncogenicity of HPV viruses
Nika Marija Lovšin, Fabio Lapenta, Urša Pečar Fonović, Katerina Jazbec, Elvira Maličev, Martina Bergant Marušič, 2023, objavljeni povzetek znanstvenega prispevka na konferenci

Ključne besede: APOBEC, HPV, oncogenicity, gene expression
Objavljeno v RUNG: 10.10.2023; Ogledov: 620; Prenosov: 9
.pdf Celotno besedilo (7,73 MB)

6.
Science with the Global Cosmic-ray Observatory (GCOS)
Rafael Alves Batista, M. Ahlers, Pedro Assis, Markus Gottfried Battisti, J. A. Bellido, S. Bhatnagar, K. Bismark, Teresa Bister, Martina Boháčová, Serguei Vorobiov, 2023, objavljeni znanstveni prispevek na konferenci

Opis: The Global Cosmic-ray Observatory (GCOS) is a proposed large-scale observatory for studying ultra-high-energy cosmic particles, including ultra-high-energy cosmic rays (UHECRs), photons, and neutrinos. Its primary goal is to characterise the properties of the highest-energy particles in Nature with unprecedented accuracy, and to identify their elusive sources. With an aperture at least a ten-fold larger than existing observatories, this next-generation facility should start operating after 2030, when present-day detectors will gradually cease their activities. Here we briefly review the scientific case motivating GCOS. We present the status of the project, preliminary ideas for its design, and some estimates of its capabilities.
Ključne besede: ultra-high-energy cosmic rays, UHE photons, UHE neutrinos, the Global Cosmic-ray Observatory project
Objavljeno v RUNG: 27.09.2023; Ogledov: 819; Prenosov: 5
.pdf Celotno besedilo (692,24 KB)
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7.
In vitro tumor hypoxia imaging with fluorescent covalent organic frameworks
Tina Skorjanc, Dinesh Shetty, Damjan Makuc, Gregor Mali, Martina Bergant Marušič, Matjaž Valant, 2023, objavljeni povzetek znanstvenega prispevka na konferenci

Opis: Hypoxia refers to a condition where cells and tissues experience low, inadequate levels of O2. While healthy tissues are typically supplied with sufficient O2 (normoxia), cancerous tissues commonly face hypoxia due to the tumor’s extraordinarily high demand for oxygen. Various fluorescent small-molecule probes have been designed for selective detection of hypoxia in living cells, but few nanomaterials have been investigated for this type of bioimaging. Herein, we prepare a fluorescent covalent organic framework (COF) with β-ketoenamine linkages and post-synthetically modify it to conjugate hypoxia-sensitive nitroimidazole moieties into its pores (NI-COF). Stacks of sheets in NI-COF observed under electron microscopy were exfoliated by ultrasonication, and dynamic light scattering measurements confirmed particle size of less than 200 nm. Thus-prepared material exhibited good stability in physiological conditions and low cytotoxicity in in vitro experiments. NI-COF also showed useful fluorescence properties with an emission peak at 490 nm (λex = 420 nm) at both neutral and mildly acidic pH levels that are characteristic of tumor tissues. Encouraged by the favorable properties of the material, we incubated HeLa cells pre-treated in either hypoxic or normoxic conditions with NI-COF. Fluorescence microscopy images demonstrated that the material was preferentially taken up by hypoxic cells, which showed higher fluorescence signal in their interior than cells cultured under normoxia conditions. It is anticipated that this study will stimulate further developments of COFs for imaging various biological conditions.
Ključne besede: hypoxia, fluorescence, covalent organic frameworks, imaging, tumor cells
Objavljeno v RUNG: 19.09.2023; Ogledov: 700; Prenosov: 3
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8.
APOBEC proteins play an important role in human papillomavirus infection and oncogenesis
Martina Bergant Marušič, Fabio Lapenta, Nika Lovšin, 2023, objavljeni povzetek znanstvenega prispevka na konferenci (vabljeno predavanje)

Ključne besede: HPV, APOBEC, oncogenesis, infection
Objavljeno v RUNG: 20.07.2023; Ogledov: 780; Prenosov: 7
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Covalent organic frameworks for fluorescent imaging of hypoxia
Tina Škorjanc, Dinesh Shetty, Gregor Mali, Damjan Makuc, Martina Bergant Marušič, Matjaž Valant, 2023, objavljeni povzetek znanstvenega prispevka na konferenci

Ključne besede: hypoxia, covalent organic frameworks, imaging, fluorescence, post-synthetic modification
Objavljeno v RUNG: 06.06.2023; Ogledov: 945; Prenosov: 2
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