Hair dehydroepiandrosterone in newborn beef calves from birth up to 10 months of ageMonica Probo
, Tanja Peric
, Massimo Faustini
, Alberto Prandi
, Antonella Comin
, 2018, objavljeni povzetek znanstvenega prispevka na konferenci
Opis: Although steroidogenesis in maternal, placental and fetal compartments is interdependent, the maternal and fetal hypothalamic-pituitary-adrenal (HPA) axes represent separate biological systems, with dehydroepiandrosterone (DHEA) recognized as the main fetal steroid. Fetal steroids are likely to influence development and have long-term effects on HPA function. Hair analysis represents a promising methodological approach for the non-invasive measurement of steroids, allowing for a retrospective analysis of the total exposure to steroids over time, and avoiding the influence of acute events or circadian fluctuations (Schury et al. 2017, BMC Psychiatry 17:213). Hair coat DHEA (hcD) concentrations have been investigated in cows (Peric et al. 2017, Livestock Sci 202:39–43), but no studies
have been performed on newborn calves. Hair samples of 12 beef
calves (7 males, 5 females) were collected by shaving at calving (T0) and monthly up to 10 months of age (T1-T10), only on the re-growth area. Hair DHEA was analyzed by RIA2. Statistical analysis revealed that hcD concentrations in calves were influenced by age, with higher levels at T1 and T2 compared to the other samples (p < 0.05). HcD levels were not influenced by newborn gender, birth weight and Apgar score. These data demonstrate that DHEA is quantifiable in the hair coat of newborn calves, and that hcD levels are influenced by the age of calves. The higher accumulation of DHEA was detected from birth to 2 months of age, suggesting that DHEA continues to be secreted by the newborn calf also beyond birth and could be involved in the events occurring during the first months of age.
Ključne besede: hair, dehydroepiandrosterone, cattle, calf
Objavljeno v RUNG: 09.04.2019; Ogledov: 2866; Prenosov: 0
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