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Opis: The contribution explores the avant-garde’s engagement with war through the lens of three significant civilizational conflicts: World War I, World War II, and the currently ongoing invasions of Ukraine and Palestine. Drawing directly on the literary works of Slovenian poet Srečko Kosovel, German playwright Bertolt Brecht, and Ukrainian poets Mykola Khvylovy, Victoria Amelina, and Artem Chekh, as well as Palestinian poets Najwan Darwish and Saleem Al-Naffar, the contribution examines how avant-garde literary figures respond to and are shaped by war. Spanning the three interwar and postwar periods in a comparative perspective, particular interest is placed in the tension between death and humanity as increasingly dependent on technology that cripples the human body and mind most destructively in times of war.
Ključne besede: avant-garde, death, war, Palestine, Ukraine
Objavljeno v RUNG: 10.12.2024; Ogledov: 269; Prenosov: 1
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Opis: Autophagy is an evolutionary ancient process based on the activity of genes conserved from yeast to metazoan taxa. Whereas its role as a mechanism to provide energy during cell starvation is commonly accepted, debate continues about the occurrence of autophagy as a means specifically activated to achieve cell death. The IPLB-LdFB insect cell line, derived from the larval fat body of the lepidoptera Lymantria dispar, represents a suitable model to address this question, as both autophagic and apoptotic cell death can be induced by various stimuli. Using morphological and functional approaches, we have observed that the culture medium conditioned by IPLB-LdFB cells committed to death by the ATPase inhibitor oligomycin A stimulates autophagic cell death in untreated IPLB-LdFB cells. Moreover, proteomic analysis of the conditioned media suggests that, in IPLB-LdFB cells, oligomycin A promotes a shift towards lipid metabolism, increases oxidative stress and specifically directs the cells towards autophagic activity.
Ključne besede: Autophagic cell death, Fat body, IDGF, IPLB-LdFB, Proteomics
Objavljeno v RUNG: 23.08.2019; Ogledov: 3843; Prenosov: 0
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