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Naslov:Treatment strategies targeting persister cell formation in bacterial pathogens
Avtorji:ID Khan, Fazlurrahman (Avtor)
ID Pham, Dung (Avtor)
ID Tabassum, Nazia (Avtor)
ID Oloketuyi, Sandra (Avtor)
ID Kim, Young-Mog (Avtor)
Datoteke: Gradivo nima datotek, ki so prostodostopne za javnost. Gradivo je morda fizično dosegljivo v knjižnici fakultete, zalogo lahko preverite v COBISS-u. Povezava se odpre v novem oknu
Jezik:Angleški jezik
Vrsta gradiva:Delo ni kategorizirano
Tipologija:1.02 - Pregledni znanstveni članek
Organizacija:UNG - Univerza v Novi Gorici
Opis:Persister cells are transiently antibiotic-tolerant and dormant subpopulations that are produced to escape the effects of antibiotics within biofilms or planktonic cell populations. Persister cells are of high clinical importance due to their tolerance to antimicrobial agents and subsequent failure in antibiotic treatments. Understanding persister cell formation mechanisms is therefore highly important for developing effective therapeutic strategies against pathogenic bacterial persisters. Several anti-persister compounds have been previously identified via isolation from natural resources or chemical synthesis. Furthermore, a combination of these compounds with antibiotics or non-antibiotic drugs also allows action on multiple targets while reducing the administration frequency. Here, we present a comprehensive overview of the clinical importance and formation mechanisms of persister cells as well as the current treatment strategies against persister cell formations in chronic infections.
Ključne besede:Biofilm, anti-persister agents, persister cells, pathogenic bacteria, chronic infections
Leto izida:2020
Št. strani:665-688
Številčenje:6, 46
PID:20.500.12556/RUNG-6203 Novo okno
COBISS.SI-ID:47104259 Novo okno
DOI:10.1080/1040841X.2020.1822278 Novo okno
NUK URN:URN:SI:UNG:REP:P60IPYY7
Datum objave v RUNG:14.01.2021
Število ogledov:4488
Število prenosov:0
Metapodatki:XML DC-XML DC-RDF
:
KHAN, Fazlurrahman, PHAM, Dung, TABASSUM, Nazia, OLOKETUYI, Sandra in KIM, Young-Mog, 2020, Treatment strategies targeting persister cell formation in bacterial pathogens. Critical Reviews in Microbiology [na spletu]. 2020. Vol. 6, no. 46, p. 665–688. [Dostopano 1 april 2025]. DOI 10.1080/1040841X.2020.1822278. Pridobljeno s: https://repozitorij.ung.si/IzpisGradiva.php?lang=slv&id=6203
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Gradivo je del revije

Naslov:Critical Reviews in Microbiology
Leto izida:2020

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