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Naslov:Untargeted molecular analysis of exhaled breath as a diagnostic test for ventilator-associated lower respiratory tract infections (BreathDx)
Avtorji:ID Oort, Pouline M. van (Avtor)
ID Nijsen, Tamara M. E. (Avtor)
ID White, Iain R. (Avtor)
ID Knobel, Hugo (Avtor)
ID Felton, Timothy (Avtor)
ID Rattray, Nicholas J. W. (Avtor)
ID Lawal, Oluwasola (Avtor)
ID Bulut, Murtaza (Avtor)
ID Ahmed, Waqar (Avtor)
ID Artigas, Antonio (Avtor)
Datoteke: Gradivo nima datotek, ki so prostodostopne za javnost. Gradivo je morda fizično dosegljivo v knjižnici fakultete, zalogo lahko preverite v COBISS-u. Povezava se odpre v novem oknu
Jezik:Angleški jezik
Vrsta gradiva:Neznano
Tipologija:1.03 - Drugi znanstveni članki
Organizacija:UNG - Univerza v Novi Gorici
Opis:Patients suspected of ventilator-associated lower respiratory tract infections (VA-LRTIs) commonly receive broad-spectrum antimicrobial therapy unnecessarily. We tested whether exhaled breath analysis can discriminate between patients suspected of VA-LRTI with confirmed infection, from patients with negative cultures. Breath from 108 patients suspected of VA-LRTI was analysed by gas chromatography-mass spectrometry. The breath test had a sensitivity of 98% at a specificity of 49%, confirmed with a second analytical method. The breath test had a negative predictive value of 96% and excluded pneumonia in half of the patients with negative cultures. Trial registration number: UKCRN ID number 19086, registered May 2015.
Ključne besede:ventilator-associated pneumonia, breath analysis, volatile organic compounds, metabolomics, intensive care, hospital acquired infections
Leto izida:2021
Št. strani:str. 1-3
Številčenje:Vol. , iss.
PID:20.500.12556/RUNG-6723 Novo okno
COBISS.SI-ID:75487235 Novo okno
UDK:616.2
ISSN pri članku:0040-6376
DOI:10.1136/thoraxjnl-2021-217362 Novo okno
NUK URN:URN:SI:UNG:REP:PVOIQNHM
Datum objave v RUNG:07.09.2021
Število ogledov:4317
Število prenosov:0
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Gradivo je del revije

Naslov:Thorax
Skrajšan naslov:Thorax
Založnik:British Medical Association
ISSN:0040-6376
COBISS.SI-ID:5412615 Novo okno

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