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41.
The effect of lexical deficits on narrative disturbances in fluent aphasia
Sara Andreetta, Andrea Marini, 2015, izvirni znanstveni članek

Opis: Background: The label “fluent aphasia” applies to different aphasic syndromes char- acterised by fluent speech with difficulties in lexical retrieval and/or grammatical processing. Aims: This study aims at investigating microlinguistic and macrolinguistic skills in persons with fluent aphasia. We hypothesised that their lexical and syntactic (i.e., microlinguistic) difficulties would affect also their narrative (i.e., macrolinguistic) skills. Methods & Procedures: Growing evidence shows that traditional tests may not be sensitive enough to capture the patterns of the linguistic impairments observed in these persons. Therefore, we used a narrative task to elicit linguistic samples. Spontaneous speech was elicited through a picture description task. The narrative samples were analysed with a multilevel approach that allows clinicians to quantify their productivity levels as well as their lexical, grammatical, and narrative skills. The spontaneous speech produced by a group of 20 persons with fluent aphasia was compared to that of a group of 20 healthy participants. All participants with aphasia were in the phase of neurological stability. The two groups were matched for age and level of formal education. Outcomes & Results: Results showed that the lexical impairment observed in the group of participants with fluent aphasia hampered the ability to produce well-formed sentences that, in turn, lowered the levels of cohesion of their narrative samples. Furthermore, the reduced levels of lexical informativeness were found correlated also to the production of errors of global coherence. Conclusions: These findings support the hypothesis that in these patients, microlin- guistic difficulties might affect macrolinguistic processing. Furthermore, these results stress the importance of a multilevel approach to assess linguistic skills in patients with fluent aphasia, as it assesses both microlinguistic and macrolinguistic dimensions in parallel. Therefore, it allows linguists, psychologists, and clinicians to observe how the linguistic levels interact during natural language processing.
Ključne besede: neurolinguistics, aphasia, discourse analysis, coherence
Objavljeno v RUNG: 07.03.2016; Ogledov: 4597; Prenosov: 0
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42.
Combined fit of spectrum and composition data as measured by the Pierre Auger Observatory
Andrea Di Matteo, Andrej Filipčič, Gašper Kukec Mezek, Ahmed Saleh, Samo Stanič, Marta Trini, Darko Veberič, Serguei Vorobiov, Lili Yang, Danilo Zavrtanik, Marko Zavrtanik, 2015, objavljeni znanstveni prispevek na konferenci

Opis: We present a combined fit of both flux and composition of ultra-high energy cosmic rays as measured by the Pierre Auger Observatory. The fit has been performed for energies above 5 × 10[sup]18 eV, i.e. the region of the all-particle spectrum above the so-called “ankle” feature. A simple astrophysical model consisting of identical sources has been adopted, where nuclei are injected with a rigidity dependent mechanism and the sources are uniformly distributed in a comoving volume. The fit results suggest a source model characterized by relatively low maximum injection energies and hard spectral indices. The impact of different sources of systematic uncertainties in the above result is discussed.
Ključne besede: Pierre Auger Observatory, ultra-high energy cosmic rays, energy spectrum, elemental composition, combined data fit
Objavljeno v RUNG: 03.03.2016; Ogledov: 4587; Prenosov: 231
.pdf Celotno besedilo (704,98 KB)

43.
Reducing treatments in cattle superovulation protocols by combining a pituitary extract with a 5% hyaluronan solution: Is it able to diminish activation of the hypothalamic pituitary adrenal axis compared to the traditional protocol?
Andrea Biancucci, Tatiana Sbaragli, Antonella Comin, Lakamy Sylla, Maurizio Monaci, Tanja Peric, Giuseppe Stradaioli, 2016, izvirni znanstveni članek

Opis: Traditional superovulation protocols that include multiple gonadotropin treatments are time-consuming and labor intensive. These protocols require multiple handling and restraining of embryo donors. This will likely increase the risks of injuries in both animals and humans and induce stress that may lead to a reduced superovulatory response. These are more evident when working with cattle that are rarely handled or raised on extensive grazing. The objectives of this experiment were to compare the efficacy of a split-injection protocol of porcine pituitary-derived porcine FSH (pFSH) preparation (slow release [SR] group) to the traditional 4-day treatment with pFSH administered twice daily (C group) and to determine the concentrations of cortisol in the hair as a marker of activation of the hypothalamic-pituitary-adrenal (HPA) axis during the two superovulatory treatments. Thirty-two heifers were stimulated twice in a 2 × 2 crossover design and compared for ovarian response and numbers and characteristics of recovered ova-embryo among treatments. No differences between SR and C groups were found in terms of percentage of responsive animals (100% vs. 93.8%) and ovulation rate (83.7 ± 1.1 vs. 79.5 ± 1.0%). A positive correlation was found between the number of follicles responsive to pFSH (2-8 mm) at the beginning of treatments and the superovulatory response, and no differences were found in these follicular populations between the two treatment groups. The numbers of CLs, ova-embryos, fertilized ova, transferable and freezable embryos recovered per cow were found to be significantly higher in SR compared with C group (14.0 ± 1.6 vs. 10.6 ± 1.0, 12.1 ± 1.6 vs. 7.6 ± 1.0, 11.1 ± 1.1 vs. 7.3 ± 1.0, 9.6 ± 1.4 vs. 6.6 ± 1.0, and 9.4 ± 1.4 vs. 6.0 ± 1.0 for SR and C group, respectively). The SR group produced also a significantly greater number of excellent- and/or good-quality embryos compared with the C group. The concentrations of cortisol in the hair at Days 14 and 21 were significantly greater in the C compared with the SR group (P < 0.05). In conclusion, these results indicate that the dilution of gonadotropin in a 5% hyaluronan solution, reducing the administration frequency, improves the quantitative and qualitative superovulatory response of Marchigiana heifers. Further studies using other breeds of cattle are needed to verify the results herein obtained and to confirm the lower activation of the hypothalamic-pituitary-adrenal axis caused in the donor by the split-injection protocol.
Ključne besede: Beef heifer, Bovine, Hair cortisol, Hyaluronic acid, Slow release, Superovulation
Objavljeno v RUNG: 01.03.2016; Ogledov: 4561; Prenosov: 312
.pdf Celotno besedilo (403,15 KB)
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44.
Optimizacija optičnega nadzora naprave za površinsko montažo elektronskih komponent
Andrea Torroni, 2015, diplomsko delo

Opis: Namen diplomskega dela je odpravljanje napak na liniji za površinsko montažo elektronskih komponent (SMD). Delo na tej liniji je pokazalo, da so na izdelkih prisotne napake. Te zaradi problematičnega reševanja nepravilnosti zaustavljajo celotni proizvodni proces, za odpravljanje pa se porabi veliko časa. Proces ni več popolnoma avtomatski, kot se za to linijo zahteva. Težave nastajajo predvsem zaradi velikega števila težko predvidljivih vzrokov, ki povzročajo napake. Te lahko nastajajo na vseh napravah linije, glede na nastanek pa jih lahko zberemo v skupine. S pomočjo nekaterih izdelkov bomo analizirali vse najpogostejše napake. Raziskali bomo realne vzroke za nepravilnosti na vseh napravah na liniji in opisali rešitve za nastale težave. Te bomo z lastnimi izkušnjami tudi utemeljili. S tem delom si bodo lahko operaterji in drugi, ki jih zanima delo na tej liniji, pomagali pri reševanju napak. Opisi reševanja napak naj bi operaterje vodili k hitremu in trajnemu odpravljanju napak. Ocenili bomo, kolikšne so časovne izgube zaradi nepravilnosti oziroma kolikšen delež časovne optimizacije lahko dosežemo z odpravljanjem določenega števila napak. Cilj je doseči vsaj 5-% časovno izboljšavo na celotni proizvodnji elektronskih vezij. To bo za podjetje pomenilo znaten prihranek. Delo bo prineslo tudi nova zavedanja o pomembnosti odpravljanja napak na liniji.
Ključne besede: elektronika, površinska montaža elementov, avtomatska optična inšpekcija, napake, izboljšave
Objavljeno v RUNG: 05.10.2015; Ogledov: 6758; Prenosov: 290
.pdf Celotno besedilo (1,75 MB)

45.
An RNA-based therapeutic approach for inherited mis-splicing diseases : dissertation
Andrea Dal Mas, 2014, doktorska disertacija

Ključne besede: eksoni, genetika, mutacije, spajanje, disertacije
Objavljeno v RUNG: 22.01.2015; Ogledov: 4629; Prenosov: 172
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48.
Molecular physiology of P2X[sub]3 receptors
Andrea Nistri, Rashid Giniatullin, Elsa Fabbretti, Elena Sokolova, Alessandro Fabbro, 2006, objavljeni povzetek znanstvenega prispevka na konferenci

Ključne besede: bolečina, purinergični receptorji, signalizacija
Objavljeno v RUNG: 15.10.2013; Ogledov: 9650; Prenosov: 30
URL Povezava na celotno besedilo

49.
Cross-presentation and cancer immunotherapy
Andrea Predonzani, 2012, doktorska disertacija

Ključne besede: imunski sistem, dendritične celice, imunski odziv, tumorski antigeni, imunizacija, epidermalni rastni faktor, receptorji
Objavljeno v RUNG: 15.10.2013; Ogledov: 6160; Prenosov: 392
URL Povezava na celotno besedilo
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50.
Functional responses of P2X3 receptors of trigeminal sensory neurons from CGRP knock-out mice
S. K. Hullugundi, Rita Abbate, Alessia Franceschini, Andrea Nistri, Elsa Fabbretti, 2012, objavljeni povzetek znanstvenega prispevka na konferenci

Ključne besede: migrena, glavoboli, nevropeptidi
Objavljeno v RUNG: 15.10.2013; Ogledov: 7259; Prenosov: 27
URL Povezava na celotno besedilo

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