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5396. Prospects for Indirect Dark Matter Searches with the Cherenkov Telescope Array (CTA)John Carr, Gabrijela Zaharijas, 2015, published scientific conference contribution Abstract: The Cherenkov Telescope Array (CTA) will have a unique chance of discovery for a large range of masses in Weakly Interacting Massive Particles models of dark matter. The principal target for dark matter searches with CTA is the centre of the Galactic Halo. The best strategy is to perform CTA observations within a few degrees of the Galactic Centre, with the Galactic Centre itself and the most intense diffuse emission regions removed from the analysis. Assuming a cuspy dark matter density profile for the Milky Way, 500 hours of observations in this region provide sensitivities to and below the thermal cross-section of dark matter annihilations, for masses between a few hundred GeV and a few tens of TeV; therefore CTA will have a significant chance of discovery in some models. Since the dark matter density in the Milky Way is far from certain in the inner kpc region, other targets are also proposed for observation, like ultra-faint dwarf galaxies such as Segue 1 with 100 hours per year proposed. Beyond these two observational targets, further alternatives, such as Galactic dark clumps, will be considered closer to the actual date of CTA operations. Sensitivity predictions for dark matter searches are given on the various targets taking into account the latest instrument response functions expected for CTA together with a discussion on the systematic uncertainties from the backgrounds.
Keywords: dark matter, gamma-ray astronomy
Published in RUNG: 01.03.2016; Views: 4677; Downloads: 230
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5399. Reducing treatments in cattle superovulation protocols by combining a pituitary extract with a 5% hyaluronan solution: Is it able to diminish activation of the hypothalamic pituitary adrenal axis compared to the traditional protocol?Andrea Biancucci, Tatiana Sbaragli, Antonella Comin, Lakamy Sylla, Maurizio Monaci, Tanja Peric, Giuseppe Stradaioli, 2016, original scientific article Abstract: Traditional superovulation protocols that include multiple gonadotropin treatments are time-consuming and labor intensive. These protocols require multiple handling and restraining of embryo donors. This will likely increase the risks of injuries in both animals and humans and induce stress that may lead to a reduced superovulatory response. These are more evident when working with cattle that are rarely handled or raised on extensive grazing. The objectives of this experiment were to compare the efficacy of a split-injection protocol of porcine pituitary-derived porcine FSH (pFSH) preparation (slow release [SR] group) to the traditional 4-day treatment with pFSH administered twice daily (C group) and to determine the concentrations of cortisol in the hair as a marker of activation of the hypothalamic-pituitary-adrenal (HPA) axis during the two superovulatory treatments. Thirty-two heifers were stimulated twice in a 2 × 2 crossover design and compared for ovarian response and numbers and characteristics of recovered ova-embryo among treatments. No differences between SR and C groups were found in terms of percentage of responsive animals (100% vs. 93.8%) and ovulation rate (83.7 ± 1.1 vs. 79.5 ± 1.0%). A positive correlation was found between the number of follicles responsive to pFSH (2-8 mm) at the beginning of treatments and the superovulatory response, and no differences were found in these follicular populations between the two treatment groups. The numbers of CLs, ova-embryos, fertilized ova, transferable and freezable embryos recovered per cow were found to be significantly higher in SR compared with C group (14.0 ± 1.6 vs. 10.6 ± 1.0, 12.1 ± 1.6 vs. 7.6 ± 1.0, 11.1 ± 1.1 vs. 7.3 ± 1.0, 9.6 ± 1.4 vs. 6.6 ± 1.0, and 9.4 ± 1.4 vs. 6.0 ± 1.0 for SR and C group, respectively). The SR group produced also a significantly greater number of excellent- and/or good-quality embryos compared with the C group. The concentrations of cortisol in the hair at Days 14 and 21 were significantly greater in the C compared with the SR group (P < 0.05). In conclusion, these results indicate that the dilution of gonadotropin in a 5% hyaluronan solution, reducing the administration frequency, improves the quantitative and qualitative superovulatory response of Marchigiana heifers. Further studies using other breeds of cattle are needed to verify the results herein obtained and to confirm the lower activation of the hypothalamic-pituitary-adrenal axis caused in the donor by the split-injection protocol.
Keywords: Beef heifer, Bovine, Hair cortisol, Hyaluronic acid, Slow release, Superovulation
Published in RUNG: 01.03.2016; Views: 4567; Downloads: 312
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5400. Prototype muon detectors for the AMIGA component of the Pierre Auger ObservatoryA. Aab, Andrej Filipčič, Gašper Kukec Mezek, Ahmed Saleh, Samo Stanič, Marta Trini, Serguei Vorobiov, Lili Yang, Danilo Zavrtanik, Marko Zavrtanik, 2015, original scientific article Keywords: detektor mionov, detektor Čerenkova, AMIGA, P. Auger Observatory
Published in RUNG: 29.02.2016; Views: 5381; Downloads: 0
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