Iskanje po repozitoriju

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Ključne besede: slovenske antropologinje, kulturna antropologija, Paragvaj
Objavljeno v RUNG: 19.01.2021; Ogledov: 2253; Prenosov: 0

Opis: V prispevku o prevodu razmišljam kot enem temeljnih elementov globalizacije in svetovnega knjižnega trga (Villa) in predstavljam podatke o prevodih slovenskih mladinskih avtorjev v tuje jezike, ki jih zajemam iz različnih virov: Cobissa, Baze prevodov Javne agencije za knjigo, Trubarjevega sklada pri Društvu slovenskih pisateljev, Centra za slovensko književnost, ki jih dopolnjujem s podatki slovenskih založb. Pri njihovi organizaciji in predstavitvi upoštevam spoznanja polisitemske teorije, predvsem teh, ki se najbolj neposredno tičejo prevajanja (Even-Zohar, Shavit, Dović). V tem kontekstu me zanima tudi primerjava med prevodi slovenskih avtorjev v periferne, centralne, supercentralne jezike ter hipercentralni jezik (De Swan), pa tudi število prevodov mladinske književnosti v primerjavi s prevodi nemladinskih besedil. Kolikor bo mogoče bom opozorila tudi na morebitne izpričane odmeve v tuje jezike prevedenih slovenskih avtorjev.
Ključne besede: prevajanje, slovenska literatura, recepcija, sistemska teorija
Objavljeno v RUNG: 19.01.2021; Ogledov: 2358; Prenosov: 0
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Opis: prevod spremne besede Jadranke Šturm Kocjan ter podatkov o avtorju; knjigo v fizični obliki dostavim
Ključne besede: španščina, prevod, spremne besede
Objavljeno v RUNG: 19.01.2021; Ogledov: 2330; Prenosov: 0

Opis: The increase in antibiotic resistance of pathogenic bacteria has led to the development of new therapeutic approaches to inhibit biofilm formation as well as interfere quorum sensing (QS) signaling systems. The QS system is a phenomenon in which pathogenic bacteria produce signaling molecules that are involved in cell to cell communication, production of virulence factors, biofilm maturation, and several other functions. In the natural environment, several non-pathogenic bacteria are present as mixed population along with pathogenic bacteria and they control the behavior of microbial community by producing secondary metabolites. Similarly, non-pathogenic bacteria also take advantages of the QS signaling molecule as a sole carbon source for their growth through catabolism with enzymes. Several enzymes are produced by bacteria which disrupt the biofilm architecture by degrading the composition of extracellular polymeric substances (EPS) such as exopolysaccharide, extracellular- DNA and protein. Thus, the interference of QS system by bacterial metabolic products and enzymatic catalysis, modification of the QS signaling molecules as well as enzymatic disruption of biofilm architecture have been considered as the alternative therapeutic approaches. This review article elaborates on the diversity of different bacterial species with respect to their metabolic products as well as enzymes and their molecular modes of action. The bacterial enzymes and metabolic products will open new and promising perspectives for the development of strategies against the pathogenic bacterial infections.
Ključne besede: Bacteria, biofilm, quorum sensing, inhibition, metabolites, pathogen, virulence.
Objavljeno v RUNG: 18.01.2021; Ogledov: 2456; Prenosov: 0
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Opis: Persister cells are transiently antibiotic-tolerant and dormant subpopulations that are produced to escape the effects of antibiotics within biofilms or planktonic cell populations. Persister cells are of high clinical importance due to their tolerance to antimicrobial agents and subsequent failure in antibiotic treatments. Understanding persister cell formation mechanisms is therefore highly important for developing effective therapeutic strategies against pathogenic bacterial persisters. Several anti-persister compounds have been previously identified via isolation from natural resources or chemical synthesis. Furthermore, a combination of these compounds with antibiotics or non-antibiotic drugs also allows action on multiple targets while reducing the administration frequency. Here, we present a comprehensive overview of the clinical importance and formation mechanisms of persister cells as well as the current treatment strategies against persister cell formations in chronic infections.
Ključne besede: Biofilm, anti-persister agents, persister cells, pathogenic bacteria, chronic infections
Objavljeno v RUNG: 14.01.2021; Ogledov: 2671; Prenosov: 0
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