| Title: | Increased sensitivity in proton transfer reaction mass spectrometry by incorporation of a radio frequency ion funnel |
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| Authors: | ID Barber, Shane, Department of Chemistry, University of Leicester, University Road, Leicester LE1 7RH, U.K (Author)
ID Blake, Robert S, Department of Chemistry, University of Leicester, University Road, Leicester LE1 7RH, U.K (Author)
ID White, Iain R., Department of Chemistry, University of Leicester, University Road, Leicester LE1 7RH, U.K (Author)
ID Monks, Paul S, Department of Chemistry, University of Leicester, University Road, Leicester LE1 7RH, U.K (Author)
ID Reich, Fraser, Kore Technology Limited, Cambridgeshire Business Park, Ely, Cambridgeshire CB7 4EA, United Kingdom (Author)
ID Mullock, Stephen, Kore Technology Limited, Cambridgeshire Business Park, Ely, Cambridgeshire CB7 4EA, United Kingdom (Author)
ID Ellis, Andrew M, Department of Chemistry, University of Leicester, University Road, Leicester LE1 7RH, U.K (Author) |
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| Files: |
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| Language: | English |
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| Work type: | Not categorized |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | UNG - University of Nova Gorica
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| Abstract: | A drift tube capable of simultaneously functioning as an ion funnel is demonstrated in proton transfer reaction mass spectrometry (PTR-MS) for the first time. The ion funnel enables a much higher proportion of ions to exit the drift tube and enter the mass spectrometer than would otherwise be the case. An increase in the detection sensitivity for volatile organic compounds of between 1 and 2 orders of magnitude is delivered, as demonstrated using several compounds. Other aspects of analytical performance explored in this study include the effective E/N (ratio of electric field to number density of the gas) and dynamic range over which the drift tube is operated. The dual-purpose drift tube/ion funnel can be coupled to various types of mass spectrometers to increase the detection sensitivity and may therefore offer considerable benefits in PTR-MS work. |
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| Keywords: | Analytical performance, Detection sensitivity, Drift tube, Dynamic range, Ion funnels, Proton-transfer reaction mass spectrometry, Volatile organic compounds |
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| Year of publishing: | 2012 |
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| Number of pages: | 5387-5391 |
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| Numbering: | 12, 84 |
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| PID: | 20.500.12556/RUNG-4913 |
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| COBISS.SI-ID: | 5420283 |
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| DOI: | 10.1021/ac300894t |
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| NUK URN: | URN:SI:UNG:REP:D1FD3WSB |
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| Publication date in RUNG: | 18.07.2019 |
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| Views: | 4002 |
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| Downloads: | 0 |
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