| Title: | Study of Drug Diffusion rate by beam deflection technique |
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| Authors: | ID Swapna, Mohanachandran Nair Sindhu, UNIVERSITY OF KERALA (Author), et al. |
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| Files: |
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| Language: | English |
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| Work type: | Not categorized |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | UNG - University of Nova Gorica
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| Abstract: | Drug administration is an unavoidable part of treatment. When a drug is administered orally or intravenously, it gets absorbed into the blood stream. The rate and efficiency of absorption depend on the route of
administration. When a drug is administered through the oral route, it penetrates the epithelial cells of the intestinal mucosa. The diffusion of the drug into the blood stream depends on various parameters, such as concentration, temperature, and the nature of the mucous membrane. The passive diffusion of drugs is found to obey
Fick’s law. Water soluble drugs penetrate the cell membrane through aqueous channel or pores. Hence, the
study of diffusion of drugs into the water and finally into the blood stream is important. An attempt has been made
to study the diffusion of the drug in water as 60% to 80% of human body is water. For the study of drug diffusion in
water, a commonly used cough syrup of specific gravity 1.263 is used. It is found that the diffusion rate increases
with the concentration of the drug. |
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| Keywords: | laser beam deflection, diffusion coefficient, Fick’s law, sodium chloride, syrup |
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| Publication version: | Version of Record |
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| Year of publishing: | 2017 |
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| Number of pages: | 5 |
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| Numbering: | 6, 22 |
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| PID: | 20.500.12556/RUNG-7433 |
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| COBISS.SI-ID: | 113402371 |
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| DOI: | 10.1117/1.JBO.22.6.068001 |
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| NUK URN: | URN:SI:UNG:REP:YKK5FKV1 |
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| Publication date in RUNG: | 30.06.2022 |
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| Views: | 1866 |
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| Downloads: | 0 |
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