Title: | Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations |
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Authors: | ID Bai, Zixuan (Author) ID Wang, Jiewen (Author) ID Liu, Jiaqi (Author) ID Yuan, Haibin (Author) ID Wang, Ping (Author) ID Zhang, Miao (Author) ID Feng, Yuanhang (Author) ID Cao, Xiangtong (Author) ID Cao, Xiangan (Author) ID Kang, Guangbo (Author) ID De Marco, Ario (Author) ID Huang, He (Author) |
Files: | Bispecific_Nb.pdf (8,75 MB) MD5: 1AD683046992927D8EC1D6F90C040C63
https://www.sciencedirect.com/science/article/pii/S2001037022005785?via%3Dihub
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Language: | English |
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Work type: | Unknown |
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Typology: | 1.01 - Original Scientific Article |
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Organization: | UNG - University of Nova Gorica
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Keywords: | nanobody rational design, bispecific binders, protein activity inhibition |
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Publication date: | 01.01.2023 |
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Year of publishing: | 2023 |
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Number of pages: | str. 601-613 |
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Numbering: | 21, Vol. 21 |
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PID: | 20.500.12556/RUNG-7821-96462a96-083d-dc04-f93e-26a0443b307d |
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COBISS.SI-ID: | 135868419 |
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UDC: | 577 |
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ISSN on article: | 2001-0370 |
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DOI: | 10.1016/j.csbj.2022.12.021 |
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NUK URN: | URN:SI:UNG:REP:1F2XQNGT |
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Publication date in RUNG: | 03.01.2023 |
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Views: | 2052 |
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Downloads: | 7 |
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