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Naslov:Origins of fine structure in DNA melting curves
Avtorji:ID Asatryan, Arevik V. (Avtor)
ID Benight, Albert S. (Avtor)
ID Badasyan, Artem (Avtor)
Datoteke:URL https://pubs.aip.org/aip/jcp/article/161/5/055103/3306959/Origins-of-fine-structure-in-DNA-melting-curves
 
URL https://pubs.aip.org/aip/jcp/article-pdf/doi/10.1063/5.0213526/20099060/055103_1_5.0213526.pdf
 
Jezik:Angleški jezik
Vrsta gradiva:Neznano
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:UNG - Univerza v Novi Gorici
Opis:With the help of the one-dimensional random Potts-like model, we study the origins of fine structures observed on differential melting profiles of double-stranded DNA. We theoretically assess the effects of sequence arrangement on DNA melting curves through the comparison of results for random, correlated, and block sequences. Our results re-confirm the smearing out of the fine structure with the increase in chain length for all types of sequence arrangements and suggest that the fine structure is a finite-size effect. We have found that the fine structures on melting curves of chains comprised of blocks with correlations in sequence are more persistent, probably because of increased sequence disorder the blocks introduce. Many natural DNAs show a well-expressed fine structure of melting profiles. Our results for block sequences may suggest the existence of such sequence motifs in natural DNA sequences.
Ključne besede:disordered systems, DNA melting, Potts model
Status publikacije:Objavljeno
Verzija publikacije:Objavljena publikacija
Datum objave:07.08.2024
Leto izida:2024
Št. strani:str. 1-8
Številčenje:Vol. 161, issue 5, [article no.] 055103
PID:20.500.12556/RUNG-9214 Novo okno
ISSN:0021-9606
COBISS.SI-ID:203943939 Novo okno
UDK:544
ISSN pri članku:0021-9606
eISSN:1089-7690
DOI:10.1063/5.0213526 Novo okno
NUK URN:URN:SI:UNG:REP:THEXNLJV
Datum objave v RUNG:08.08.2024
Število ogledov:1433
Število prenosov:5
Metapodatki:XML DC-XML DC-RDF
:
ASATRYAN, Arevik V., BENIGHT, Albert S. in BADASYAN, Artem, 2024, Origins of fine structure in DNA melting curves. The Journal of chemical physics [na spletu]. 2024. Vol. 161, no. 5,  055103, p. 1–8. [Dostopano 4 april 2025]. DOI 10.1063/5.0213526. Pridobljeno s: https://pubs.aip.org/aip/jcp/article-pdf/doi/10.1063/5.0213526/20099060/055103_1_5.0213526.pdf
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Gradivo je del revije

Naslov:The Journal of chemical physics
Skrajšan naslov:J. chem. phys.
Založnik:American Institute of physics
ISSN:0021-9606
COBISS.SI-ID:5253893 Novo okno

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Jezik:Slovenski jezik
Ključne besede:voda, modeli vode, struktura, termodinamika


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