| Naslov: | Origins of fine structure in DNA melting curves |
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| Avtorji: | ID Asatryan, Arevik V. (Avtor)
ID Benight, Albert S. (Avtor)
ID Badasyan, Artem (Avtor) |
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| Datoteke: |  https://pubs.aip.org/aip/jcp/article/161/5/055103/3306959/Origins-of-fine-structure-in-DNA-melting-curves
https://pubs.aip.org/aip/jcp/article-pdf/doi/10.1063/5.0213526/20099060/055103_1_5.0213526.pdf
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| Jezik: | Angleški jezik |
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| Vrsta gradiva: | Neznano |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: | UNG - Univerza v Novi Gorici
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| Opis: | With the help of the one-dimensional random Potts-like model, we study the origins of fine structures observed on differential melting profiles of double-stranded DNA. We theoretically assess the effects of sequence arrangement on DNA melting curves through the comparison of results for random, correlated, and block sequences. Our results re-confirm the smearing out of the fine structure with the increase in chain length for all types of sequence arrangements and suggest that the fine structure is a finite-size effect. We have found that the fine structures on melting curves of chains comprised of blocks with correlations in sequence are more persistent, probably because of increased sequence disorder the blocks introduce. Many natural DNAs show a well-expressed fine structure of melting profiles. Our results for block sequences may suggest the existence of such sequence motifs in natural DNA sequences. |
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| Ključne besede: | disordered systems, DNA melting, Potts model |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Datum objave: | 07.08.2024 |
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| Leto izida: | 2024 |
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| Št. strani: | str. 1-8 |
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| Številčenje: | Vol. 161, issue 5, [article no.] 055103 |
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| PID: | 20.500.12556/RUNG-9214  |
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| ISSN: | 0021-9606 |
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| COBISS.SI-ID: | 203943939 |
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| UDK: | 544 |
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| ISSN pri članku: | 0021-9606 |
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| eISSN: | 1089-7690 |
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| DOI: | 10.1063/5.0213526 |
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| NUK URN: | URN:SI:UNG:REP:THEXNLJV |
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| Datum objave v RUNG: | 08.08.2024 |
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| Število ogledov: | 1435 |
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| Število prenosov: | 5 |
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| Metapodatki: |    |
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