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21.
Molecules involved in motility regulation in Escherichia coli cells: a review
Fazlurrahman Khan, Nazia Tabassum, Dung :Pham, Sandra Oloketuyi, Young-Mog Kim, 2020, izvirni znanstveni članek

Opis: The initial colonization of the host organism by commensal, probiotic, and pathogenic Escherichia coli strains is an important step in the development of infections and biofilms. Sensing and colonization of host cell surfaces are governed by flagellar and fimbriae/pili appendages, respectively. Biofilm formation confers great advantages on pathogenic E. coli cells such as protection against the host immune system, antimicrobial agents, and several environmental stress factors. The transition from planktonic to sessile physiological states involves several signaling cascades and factors responsible for the regulation of flagellar motility in E. coli cells. These regulatory factors have thus become important targets to control pathogenicity. Hence, attenuation of flagellar motility is considered a potential therapy against pathogenic E. coli. The present review describes signaling pathways and proteins involved in direct or indirect regulation of flagellar motility. Furthermore, application strategies for antimotility natural or synthetic compounds are discussed also.
Najdeno v: osebi
Ključne besede: Biofilm formation, Escherichia coli, inhibition, motility, pathogenesis
Objavljeno: 14.01.2021; Ogledov: 1701; Prenosov: 0
.pdf Polno besedilo (2,42 MB)

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CDR1 composition can affect nanobody recombinant expression yields
Marco Orlando, Sara Fortuna, Sandra Oloketuyi, Gregor Bajc, Adi Goldenzweig, Ario de Marco, 2021, izvirni znanstveni članek

Najdeno v: osebi
Ključne besede: nanobodies, in silico engineering, mutagenesis
Objavljeno: 15.09.2021; Ogledov: 706; Prenosov: 22
.pdf Polno besedilo (2,37 MB)

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