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Univerza v Novi Gorici
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ENG
Naslov:
WATER-POLYPEPTIDE INTERACTION IN CLASSICAL MODELS OF HELIX-COIL TRANSITION
Avtorji:
ID
Badasyan, Artem
(Mentor)
Več o mentorju...
ID
Yeritsyan, Knarik
(Avtor)
Datoteke:
Knarik_Yeritsyan.pdf
(1,70 MB)
MD5: A467D4551EAF7FA698AB28FB2743BD4D
Jezik:
Angleški jezik
Vrsta gradiva:
Diplomsko delo/naloga
Tipologija:
2.11 - Diplomsko delo
Organizacija:
FN - Fakulteta za naravoslovje
Opis:
Zimm-Bragg model is the simplest to describe the conformational transitions in biopolymers and is regularly used for preocessing the experimental data. We review the model and its Hamiltonian definition with the goal to introduce the interaction with water into the picture. We show how modified ZB model with the account of water-polypeptide interactions allows to describe both cold denaturation and helix-coil transition and derive such the formula explicitly. The obtained theoretical expression for the helicity degree contains two independent parameters that can be fitted with the experimental data to determine the parameters of cold denaturation and helix-coil transition from a single fit and for a single set of experimental data.
Ključne besede:
Zimm-Bragg model
,
conformational transitions in biopolymers
,
cold denaturation
Kraj izida:
Nova Gorica
Leto izida:
2016
PID:
20.500.12556/RUNG-2515
COBISS.SI-ID:
4512763
NUK URN:
URN:SI:UNG:REP:G9A5Q0OH
Datum objave v RUNG:
28.09.2016
Število ogledov:
8747
Število prenosov:
281
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