Repozitorij Univerze v Novi Gorici

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Naslov:Treatment strategies targeting persister cell formation in bacterial pathogens
Avtorji:Khan, Fazlurrahman (Avtor)
Pham, Dung (Avtor)
Tabassum, Nazia (Avtor)
Oloketuyi, Sandra (Avtor)
Kim, Young-Mog (Avtor)
Datoteke:Gradivo nima datotek. Gradivo je morda fizično dosegljivo v knjižnici fakultete, zalogo lahko preverite v COBISS-u. Povezava se odpre v novem oknu
Jezik:Angleški jezik
Vrsta gradiva:Delo ni kategorizirano (r6)
Tipologija:1.02 - Pregledni znanstveni članek
Organizacija:UNG - Univerza v Novi Gorici
Opis:Persister cells are transiently antibiotic-tolerant and dormant subpopulations that are produced to escape the effects of antibiotics within biofilms or planktonic cell populations. Persister cells are of high clinical importance due to their tolerance to antimicrobial agents and subsequent failure in antibiotic treatments. Understanding persister cell formation mechanisms is therefore highly important for developing effective therapeutic strategies against pathogenic bacterial persisters. Several anti-persister compounds have been previously identified via isolation from natural resources or chemical synthesis. Furthermore, a combination of these compounds with antibiotics or non-antibiotic drugs also allows action on multiple targets while reducing the administration frequency. Here, we present a comprehensive overview of the clinical importance and formation mechanisms of persister cells as well as the current treatment strategies against persister cell formations in chronic infections.
Ključne besede:Biofilm, anti-persister agents, persister cells, pathogenic bacteria, chronic infections
Leto izida:2020
Št. strani:665-688
Številčenje:46, 6
COBISS_ID:47104259  Povezava se odpre v novem oknu
URN:URN:SI:UNG:REP:P60IPYY7
DOI:10.1080/1040841X.2020.1822278 Povezava se odpre v novem oknu
Število ogledov:1125
Število prenosov:0
Metapodatki:XML RDF-CHPDL DC-XML DC-RDF
Področja:Gradivo ni uvrščeno v področja.
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Skupna ocena:(0 glasov)
Vaša ocena:Ocenjevanje je dovoljeno samo prijavljenim uporabnikom.

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Gradivo je del revije

Naslov:Critical Reviews in Microbiology
Leto izida:2020

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