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Abstract: Capturing the dynamic electronic band structure of a correlated material presents a powerful capability for uncovering the complex couplings between the electronic and structural degrees of freedom. When combined with ultrafast laser excitation, new phases of matter can result, since far-from-equilibrium excited states are instantaneously populated. Here, we elucidate a general relation between ultrafast non-equilibrium electron dynamics and the size of the characteristic energy gap in a correlated electron material. We show that carrier multiplication via impact ionization can be one of the most important processes in a gapped material, and that the speed of carrier multiplication critically depends on the size of the energy gap. In the case of the charge-density wave material 1T-TiSe 2 , our data indicate that carrier multiplication and gap dynamics mutually amplify each other, which explains—on a microscopic level—the extremely fast response of this material to ultrafast optical excitation. Self-amplified photo-induced gap quenching in a correlated electron material. Available from: https://www.researchgate.net/publication/308804379_Self-amplified_photo-induced_gap_quenching_in_a_correlated_electron_material [accessed Apr 20, 2017].
Keywords: high harmonic generation, charge-density wave material, 1T-TiSe2, non-equilibrium electron dynamics, ultrafast surface science
Published in RUNG: 20.04.2017; Views: 5540; Downloads: 0
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Abstract: Monoclonal antibodies specific for biomarkers expressed on the surface of uveal melanoma (UM) cells would simplify the immune-capture and genomic characterization of heterogeneous tumor cells originated from patient derived xenografts (PDXs). Antibodies against four independent tumor antigens were isolated by panning a nanobody synthetic library. Such antibodies enabled flow-cytometry-based sorting of distinct cell sub-populations from UM PDXs and to analyze their genomic features. The complexity and specificity of the biochemical and genomic biomarker combinations mirrored the UM tumor polyclonality. The data showed that MUC18 is highly and universally displayed at the surface of UM cells with different genetic background and consequently represents a reliable pan-biomarker for their identification and purification. In contrast, the other three biomarkers were detected in very variable combinations in UM PDX cells. The availability of the identified nanobodies will be instrumental in developing clone-specific drug evaluation and rational clinical strategies based on accurate genomic profiling
Keywords: nanobodies, uveal melanoma, patient derived xenografts, MUC18, membrane surface biomarkers, panning, tumor polyclonality
Published in RUNG: 19.04.2017; Views: 5580; Downloads: 0
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Keywords: Zelen (Vitis vinifera L.), targeted metabolomics, wine aroma, sensory evaluation, alternative vinification procedures
Published in RUNG: 18.04.2017; Views: 5129; Downloads: 0
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Keywords: ultra high energy (UHE) cosmic rays, cosmic ray experiments, Pierre Auger Observatory, UHE photon search
Published in RUNG: 13.04.2017; Views: 4070; Downloads: 0
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Abstract: Semi-structured interviews with grantees and successful CEEPUS network coordinators have done via skype or telephone. The interview partners have been selected by the National CEEPUS Offices (NCOs) and the Secretary General of CEEPUS. The “best of” of the interviews are presented in the document at hand. The provided material can be used as basis for promotion (e.g. for a brochure or for the CEEPUS web-page) to highlight successful CEEPUS cases. Furthermore, based on the analyses, further recommendations are given on how to reach a better visibility of CEEPUS outcomes and impact.
Keywords: interview, CEEPUS, academic, mobility
Published in RUNG: 10.04.2017; Views: 4321; Downloads: 0
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