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Abstract: Teoretični del diplomske naloge zajema in obravnava začasni eksperimentalni prostor PLATOON Kunsthalle Berlin kot socialno skulpturo. Uvodno temo odprem z razlago, zakaj sem izbrala PLATOON Kunsthalle Berlin za vsebino te diplomske naloge ter jo na kratko predstavim. Sledi definicija pojma socialne skulpture ter predstavitev Josepha Beuysa, umetnika, ki je izraz prvi uporabil. Za tem povežem in kategoriziram PLATOON Kunsthalle kot socialno skulpturo, jo podrobno predstavim od ustanovitve do postavitve v Berlinu, obdelam njeno skupnost in opišem njen vpliv na berlinsko umetniško sceno ter orišem organizacijo PLATOON Cultural Development. Praktični del tega diplomskega dela je video inštalacija EAT MEAT?, v kateri si postavljam vprašanja o morali, družbi ter o odnosu do živali. Na podlagi Freudove delitve osebnosti raziskujem človeško - živalske odnose in človekovo moralno vlogo v teh odnosih ter vlečem vzporednice med vrednotami. Inštalacija je avtobiografsko delo, intimno in subjektivno. Njen namen je vzbuditi zavedanje in razmislek o tem, v kakšni družbi pravzaprav živimo, kakšne posledice puščajo naša dejanja in udobje, ker oboje nam vsiljuje ignoranca industrije v svojem brezkompromisnem boju za zaslužek.
Keywords: PLATOON, Kunsthalle, Berlin, socialna skulptura, eksperimentalni prostor, umetniška scena, video inštalacija, družba, morala, meso, srce
Published in RUNG: 01.02.2017; Views: 5447; Downloads: 199
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Abstract: In vitro selection of antibodies allows to obtain highly functional binders, rapidly and at lower cost. Here, we describe the first fully synthetic phage display library of humanized llama single domain antibody (NaLi-H1: Nanobody Library Humanized 1). Based on a humanized synthetic single domain antibody (hs2dAb) scaffold optimized for intracellular stability, the highly diverse library provides high affinity binders without animal immunization. NaLi-H1 was screened following several selection schemes against various targets (Fluorescent proteins, actin, tubulin, p53, HP1). Conformation antibodies against active RHO GTPase were also obtained. Selected hs2dAb were used in various immunoassays and were often found to be functional intrabodies, enabling tracking or inhibition of endogenous targets. Functionalization of intrabodies allowed specific protein knockdown in living cells. Finally, direct selection against the surface of tumor cells produced hs2dAb directed against tumor-specific antigens further highlighting the potential use of this library for therapeutic applications.
Keywords: nanobodies, synthetic phage display library, in vitro panning
Published in RUNG: 17.08.2016; Views: 5230; Downloads: 243
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Abstract: The muon content of extensive air showers is an observable sensitive to the primary composition and to the hadronic interaction properties. We present here different methods which allow us to estimate the muon number at the ground level and the muon production depth by exploiting the measurement of the longitudinal, lateral and temporal distribution of particles in air showers recorded at the Pierre Auger Observatory. The results, obtained at about 10[sup]19 eV (E[inf]CM ∼ 140 TeV center-of-mass energy for proton primaries), are compared to the predictions of LHC-tuned hadronic interaction models with different primary masses and suggest a deficit in the muon content at the ground predicted by simulations. The Pierre Auger Observatory uses water-Cherenkov detectors to measure particle densities at the ground and therefore has a good sensitivity to the muon content of air showers. Moreover, due to its hybrid design, the combination of muon measurements with other independent mass composition analyses such as Xmax provides additional constraints on hadronic interaction models.
Keywords: Pierre Auger Observatory, ultra-high energy cosmic rays, muons, mass composition, hadronic interactions
Published in RUNG: 03.03.2016; Views: 4774; Downloads: 218
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Keywords: diplomske naloge, Srednji vek, oblačilna kultura, moda
Published in RUNG: 22.01.2015; Views: 5576; Downloads: 577
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Keywords: tradicionalne beneške palače, kulturna dediščina, restavratorstvo, finančna analiza, trajnostni način, magistrske naloge
Published in RUNG: 15.10.2013; Views: 4917; Downloads: 275
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