1. Thermal lens spectrometry - still a technique on the horizon?Mladen Franko, 2015 Abstract: In 1980’s thermal lens spectrometry (TLS) was still considered as a “spectrometric technique on the horizon” as one can also read from one of the textbooks on spectrochemical analysis of that time. Intensive development of thermal lens instrumentation and methods of chemical analysis and material characterisation has however resulted in substantial progress in this field, which is evident from important instrumental innovations and first commercial instruments (i.e. thermal lens microscopes -TLM) designed for lab-on-a-chip chemistry as well as from novel applications of TLS in various areas, where highly sensitive and rapid chemical analysis of complex samples is needed, including food safety and quality control, environmental analysis and biomedical diagnostics.
This presentation is a review of most significant contributions and applications of thermal lens spectrometry, with emphasis on most recent achievements in instrumentation, which culminated into construction of novel optimized TLM instruments, capable of exploiting the tuneability of incoherent light sources and enabled novel applications particularly in micro-fluidics. Based on latest progress relying on bio-analytical assays and micro-fluidic flow injection with TLM detection we have also witnessed firs routine applications of TLS in analytical and diagnostic laboratories, which on wine side actually classifies TLS as a conventional and routine analytical tool, but at the same time opens new horizons for development and applications of this ultrasensitive and rapid spectrometric technique.
Found in: ključnih besedah
Summary of found: ...lab-on-a-chip chemistry as well as from novel applications of TLS in various areas, where highly...
Keywords: Thermal lens spectrometry, applications, Liquid chromatography, flow injection analysis, bioanalytical methods
Published: 29.03.2016; Views: 2756; Downloads: 0
 Fulltext (609,15 KB) |
2. Determination of Trace Cr(VI) with Diphenylcarbazide by μFIA–Thermal Lens MicroscopyTatyana Gor’kova, Michail Proskurnina, Mingqiang Liu, Mladen Franko, 2016, original scientific article Abstract: The optimum reaction parameters for the interaction of hexavalent chromium [Cr(VI)] with diphenylcarbazide in microfluidic
chips (μFIA) with thermal-lens microscopic detection were selected. The characteristic feature of the applied
flow scheme is the injection of the reagent into the stream containing the test metal, which enables in-field and
real-time monitoring of Cr(VI) simply by flowing the sample continuously through the microchip. The limit of detection
of Cr(VI) under the selected conditions (signal generating wavelength, 514.5 nm; excitation power, 100 mW; detection
position, 10 cm downstream from the mixing zone of the microchip; flow rate 10 μL min–1; injection volume,
1.4 μL) is 15 ng mL–1 (2.9 × 10–7 mol L–1). The linear range is 40 ng mL–1 – 10 μg mL–1 with a relative standard deviation
no higher than 10% in the concentration range 0.1–1 μg mL–1. The online monitoring by this scheme provides the
possibility of up to 360 analyses per hour.
Found in: ključnih besedah
Summary of found: ...Photothermal lensing, thermal-lens microscopic detection, microfluidic applications, μFIA, hexavalent
chromium, diphenylcarbazide...
Keywords: Photothermal lensing, thermal-lens microscopic detection, microfluidic applications, μFIA, hexavalent
chromium, diphenylcarbazide
Published: 12.12.2016; Views: 1995; Downloads: 0
Fulltext (312,62 KB) |
3. Thermal Lens Spectrometry and Microscopy Analytical Chemist’s ApproachMladen Franko, unpublished invited conference lecture Abstract: This lecture introduces the basic concepts and recent progres in theory, instrumentation and applications of thermal lens spectrometry, thermal lens microscopy and their utilization for highly sensitive, and high throughput detection in liquid chromatography, flow injectionanalysis in microfluidic systems.
Found in: ključnih besedah
Summary of found: ...and recent progres in theory, instrumentation and applications of thermal lens spectrometry, thermal lens microscopy...
Keywords: Thermal lens spectrometry, TLS microscopy, theory, applications
Published: 01.03.2017; Views: 2122; Downloads: 1
Fulltext (17,07 MB)
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