1. CDR1 composition can affect nanobody recombinant expression yieldsMarco Orlando, Sara Fortuna, Sandra Oloketuyi, Gregor Bajc, Adi Goldenzweig, Ario De Marco, 2021, original scientific article Keywords: nanobodies, in silico engineering, mutagenesis Published in RUNG: 15.09.2021; Views: 2293; Downloads: 45 Full text (2,37 MB) |
2. An anti-HER2 nanobody binds to its antigen HER2 via two independent paratopesDaniele Ubbiali, Marco Orlando, Matic Kovačič, Claudio Iacobucci, Marta S. Semrau, Gregor Bajc, Sara Fortuna, Gregor Ilc, Barbara Medagli, Sandra Oloketuyi, Ario De Marco, 2021, original scientific article Keywords: NMR, cross-linking, mass spectrometry, nanobodies, modelling, rational mutagenesis Published in RUNG: 15.04.2021; Views: 3059; Downloads: 0 This document has many files! More... |
3. Effect of Humanizing Mutations on the Stability of the Llama Single-Domain Variable RegionMiguel Soler, Barbara Medagli, Jiewen Wang, Sandra Oloketuyi, Gregor Bajc, He Huang, Sara Fortuna, Ario De Marco, 2021, original scientific article Keywords: nanobody framework, modeling, nanobody humanization, CDR grafting Published in RUNG: 27.01.2021; Views: 3016; Downloads: 68 Full text (2,00 MB) |
4. A consensus protocol for the in silico optimisation of antibody fragmentsMiguel Soler, Barbara Medagli, Marta S. Semrau, Paola Storici, Gregor Bajc, Ario De Marco, Alessandro Laio, Sara Fortuna, 2019, original scientific article Keywords: nanobodies, in silico design, Her2 Published in RUNG: 21.11.2019; Views: 3821; Downloads: 0 This document has many files! More... |
5. Comparative analysis of fusion tags used to functionalize recombinant antibodiesArio De Marco, Gianluca Veggiani, Barbara Giabbai, Marta Semrau, Barbara Medagli, Vincenzo Riccio, Gregor Bajc, Paola Storici, 2020, original scientific article Keywords: recombinant antibodies, protein production, fusion tags Published in RUNG: 30.09.2019; Views: 3583; Downloads: 70 Full text (740,27 KB) |