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2. Matrix Gla Protein and Alkaline Phosphatase Are Differently Modulated in Human Dermal Fibroblasts from PXE Patients and ControlsFederica Boraldi, Giulia Annovi, Cees Vermeer, Leon J. Schurgers, Tommaso Trenti, Roberta Tiozzo, Deanna Guerra, Daniela Quaglino, 2013, original scientific article Keywords: Fibroblast, Vitamin K, Elastin calcification, Proteomics
Published in RUNG: 23.08.2019; Views: 4848; Downloads: 0
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3. Ectopic calcification in β-thalassemia patients is associated with increased oxidative stress and lower MGP carboxylationFederica Boraldi, Maria Immaculada Garcia Fernandez, Chiara Paolinelli DeVincenzi, Giulia Annovi, Leon J. Schurgers, Cees Vermeer, Paolo Cianciulli, Ivonne Pasquali Ronchetti, Daniela Quaglino, 2013, original scientific article Keywords: Elastin
Oxidative stress
Matrix Gla protein
Ectopic calcification
Beta-thalassemia
Published in RUNG: 23.08.2019; Views: 4448; Downloads: 0
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4. Matrix Gla protein (MGP) is involved in elastic fiber calcification in the dermis of Pseudoxanthoma Elasticum (PXE) patients.Gheduzzi Dealba, Federica Boraldi, Annovi Giulia, Paolinelli Devincenzi Chiara, Schurgers Leon J, Vermeer Cees, Quaglino Daniela, Pasquali Ronchetti Ivonne, 2007, original scientific article Abstract: Mature MGP (Matrix g-carboxyglutamic acid protein) is known to inhibit soft connective tissues calcification. We
investigated its possible involvement in pseudoxanthoma elasticum (PXE), a genetic disorder whose clinical manifestations
are due to mineralization of elastic fibers. PXE patients have lower serum concentration of total MGP compared to
controls (Po0.001). Antibodies specific for the noncarboxylated (Glu-MGP) and for the g-carboxylated (Gla-MGP) forms of
MGP were assayed on ultrathin sections of dermis from controls and PXE patients. Normal elastic fibers in controls and
patients were slightly positive for both forms of MGP, whereas Gla-MGP was more abundant within control’s than within
patient’s elastic fibers (Po0.001). In patients’ calcified elastic fibers, Glu-MGP intensively colocalized with mineral
precipitates, whereas Gla-MGP precisely localized at the mineralization front. Data suggest that MGP is present within
elastic fibers and is associated with calcification of dermal elastic fibers in PXE.
Keywords: calcification, dermal fibroblast, elastic fiber, human skin, MGP, pseudoxanthoma elasticum
Published in RUNG: 22.07.2019; Views: 4546; Downloads: 0
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5. Neutron irradiation effects on the structural properties of KU1, KS-4V and I301 silica glassesM. León, Luigi Giacomazzi, Sylvain Girard, Nicolas Richard, P. Martín, Layla Martin-Samos, A. Ibarra, A. Boukenter, Youcef Ouerdane, 2014, original scientific article Keywords: silica, defects, optical fibers, hardening
Published in RUNG: 03.10.2018; Views: 5252; Downloads: 0
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6. Postopek za predelavo papirniškega blata v bioplin in surovino za kartonLeon Kaluža, Gregor Drago Zupančič, 2014, patent Abstract: Predmetni izum se nanaša na anaerobno obdelavo aerobnega aktivnega blata in njegovo pretvorbo v bioplin. Blata kot neobdelanega substrata ni mogoče zadovoljivo pretvoriti v bioplin zaradi predolgega zadrževalnega časa za anaerobni razkroj in prenizke biorazgradljivosti. Predmetni izum predstavlja postopek za preobdelavo aerobnega blata iz proizvodnje kartona v bioplin, ki obsega najprej ustrezno hidrolizo blata, ki ji sledi predelava hidrolizata po anaerobnem postopku v UASB reaktorju. Prvi proces predstavlja tehnologijo, kjer blato solubiliziramo pri pH 12 in 70 °C, hidrolizat dodajamo v odpadno vodo in mešanico brez težav obdelamo v konvencionalnem UASB reaktorju za čiščenje papirniške odpadne vode. V tem primeru je mogoče brez težav obdelati mešanico z dodatkom hidrolizata 5(v/v) %, proizvodnjo bioplina pa povišamo za do 20 %. Trdni preostanek po hidrolizi, ki je higieniziran, je uporaben kot surovina v proizvodnji kartona, če se dodaja v primerno nizki koncentraciji 1(m/m)%, ki ne degradira bistveno lastnosti standardnih surovin.
Keywords: Aktivno blato, Bioplin, Surovina za karton
Published in RUNG: 30.03.2016; Views: 6289; Downloads: 0
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