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1. Affinity maturation of antibody fragments : a review encompassing the development from random approaches to computational rational optimization Jiaqi Liu, Guangbo Kang, Jiewen Wang, Haibin Yuan, Yili Wu, Shuxian Meng, Ping Wang, Miao Zhang, Yuli Wang, Yuanhang Feng, He Huang, Ario De Marco, 2023, review article Keywords: deep learning, protein modeling, random mutagenesis, rational mutagenesis Published in RUNG: 17.07.2023; Views: 1501; Downloads: 8 Full text (2,21 MB)

2. Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations Zixuan Bai, Jiewen Wang, Jiaqi Liu, Haibin Yuan, Ping Wang, Miao Zhang, Yuanhang Feng, Xiangtong Cao, Xiangan Cao, Guangbo Kang, Ario De Marco, He Huang, 2023, original scientific article Keywords: nanobody rational design, bispecific binders, protein activity inhibition Published in RUNG: 03.01.2023; Views: 1819; Downloads: 7 Full text (8,75 MB) This document has many files! More...

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