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1.
Study of Drug Diffusion rate by beam deflection technique
Mohanachandran Nair Sindhu Swapna, 2017, original scientific article

Abstract: Drug administration is an unavoidable part of treatment. When a drug is administered orally or intravenously, it gets absorbed into the blood stream. The rate and efficiency of absorption depend on the route of administration. When a drug is administered through the oral route, it penetrates the epithelial cells of the intestinal mucosa. The diffusion of the drug into the blood stream depends on various parameters, such as concentration, temperature, and the nature of the mucous membrane. The passive diffusion of drugs is found to obey Fick’s law. Water soluble drugs penetrate the cell membrane through aqueous channel or pores. Hence, the study of diffusion of drugs into the water and finally into the blood stream is important. An attempt has been made to study the diffusion of the drug in water as 60% to 80% of human body is water. For the study of drug diffusion in water, a commonly used cough syrup of specific gravity 1.263 is used. It is found that the diffusion rate increases with the concentration of the drug.
Keywords: laser beam deflection, diffusion coefficient, Fick’s law, sodium chloride, syrup
Published in RUNG: 30.06.2022; Views: 1255; Downloads: 0
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2.
Reply to: "Does PCNA diffusion on DNA follow a rotation-coupled translation mechanism?"
Matteo De March, Silvia Onesti, Alfredo De Biasio, 2020, review article

Keywords: PCNA, replication, diffusion, structure
Published in RUNG: 01.03.2021; Views: 2156; Downloads: 38
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4.
TLS Spectrometry & Detection in Liquid Chromatography, FIA and Microfluidic Systems
Mladen Franko, invited lecture at foreign university

Abstract: This presentation provides theoretical backround for thermal lens spectrometry (TLS) and TLS microscopy (TLM) and describes the basic instrumentation for TLS and TLM measurements. Presented applications of TLS and TLM include detection in HPLC (carotenoids, bilirubin, biliverdin), FIA (alergens, Ag, Ag+, phytoplankton and cyanobacterial pigments, organophospate pesticides) and TLM detection in microfluidic systems (Cr(VI), microcystin, NGAL, study of diffusion proceses)
Keywords: Spekrometry TLS, TLM, HPLC, FIA, microfluidics, bilirubin, biliverdin, carotenoids, alergens, mikrocystin, pigments, organophosphate pesticides, NGAL, Ag, Cr(VI), diffusion
Published in RUNG: 16.09.2016; Views: 5345; Downloads: 3
.pdf Full text (35,40 MB)

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