Repository of University of Nova Gorica

Search the repository
A+ | A- | Help | SLO | ENG

Query: search in
search in
search in
search in
* old and bologna study programme

Options:
  Reset


51 - 60 / 72
First pagePrevious page12345678Next pageLast page
51.
Pre-immune nanobody collections and their biotechnological applications
Ario De Marco, invited lecture at foreign university

Keywords: phage libraries, nanobodies, in vitro antibody panning
Published in RUNG: 17.09.2018; Views: 2957; Downloads: 0
This document has many files! More...

52.
Nanobodies as convenient reagents for multiple biotechnological applications
Ario De Marco, invited lecture at foreign university

Keywords: biomarker detection, immunocapture, nanobodies
Published in RUNG: 17.09.2018; Views: 2825; Downloads: 0
This document has many files! More...

53.
Nanobodies: a flexible technological platform
Ario De Marco, invited lecture at foreign university

Keywords: Nanobodies, immunoreagents, recombinant antibody panning
Published in RUNG: 17.09.2018; Views: 3103; Downloads: 0
This document has many files! More...

54.
Nanobodies: flexible structures for biotechnological applications
Ario De Marco, unpublished invited conference lecture

Keywords: nanobodies, in vitro panning, extracellular vesicles, oncology, toxic algae
Published in RUNG: 16.03.2018; Views: 3554; Downloads: 0
This document has many files! More...

55.
56.
57.
In vitro isolation of anti Alexandrium minutum nanobodies from a pre-immune library
Elisa Mazzega, Alfred Beran, Marina Cabrini, Ario De Marco, 2017, published scientific conference contribution abstract

Keywords: nanobodies, toxic microalgae, biopanning
Published in RUNG: 04.12.2017; Views: 4046; Downloads: 33
URL Link to full text
This document has many files! More...

58.
Engineered cross-reacting nanobodies simplify comparative oncology between humans and dogs
Elisa Mazzega, Ario De Marco, 2017, original scientific article

Keywords: HER2, nanobodies, inter-species cross-reactivity, thermophoresis
Published in RUNG: 19.10.2017; Views: 4429; Downloads: 0
This document has many files! More...

59.
Whole-cell biopanning with a synthetic phage display library of nanobodies enabled the recovery of follicle-stimulating hormone receptor inhibitors
Ronan Crepin, Gianluca Veggiani, Selma Djender, Anne Beugnet, Francois Planeix, Christophe Pichon, Sandrine Moutel, Sebastian Amigorena, Franck Pérez, Nicolae Ghinea, Ario De Marco, 2017, original scientific article

Abstract: Antibodies are essential reagents that are increasingly used in diagnostics and therapy. Their specificity and capacity to recognize their native antigen are critical characteristics for their in vivo application. Follicle-stimulating hormone receptor is a GPCR protein regulating ovarian follicular maturation and spermatogenesis. Recently, its potentiality as a cancer biomarker has been demonstrated but no antibody suitable for in vivo tumor targeting and treatment has been characterized so far. In this paper we describe the first successful attempt to recover recombinant antibodies against the FSHR and that: i) are directly panned from a pre-immune library using whole cells expressing the target receptor at their surface; ii) show inhibitory activity towards the FSH-induced cAMP accumulation; iii) do not share the same epitope with the natural binder FSH; iv) can be produced inexpensively as mono- or bivalent functional molecules in the bacterial cytoplasm. We expect that the proposed biopanning strategy will be profitable to identify useful functional antibodies for further members of the GPCR class.
Keywords: nanobodies, GPCR proteins, FSHR, panning, pre-immune antibody library
Published in RUNG: 19.10.2017; Views: 3880; Downloads: 0
This document has many files! More...

60.
Search done in 0.05 sec.
Back to top