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Title:Physics behind the Conformational Transitions in Biopolymers. Demystification of DNA melting and Protein Folding
Authors:ID Badasyan, Artem, UNG (Author)
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Language:English
Work type:Not categorized
Typology:3.14 - Invited Lecture at Foreign University
Organization:UNG - University of Nova Gorica
Abstract:Biophysics is the area of research, devoted to the studies of physical problems related to living systems. Animal cell is the smallest unit of an organism and mainly contains water solutions of structurally inhomogeneous polymers of biological origin: polypeptides (proteins) and polynucleotides (DNA, RNA). Statistical physics of macromolecules allows to describe the conformations of both synthetic and bio-polymers and constitutes the basis of Biophysics. During the talk I will report on the biophysical problems I have solved with numerical simulations (Langevin-based Molecular Dynamics of Go-like protein folding model and Monte Carlo with Wang-Landau sampling) and analytical studies of spin models (formula evaluation by hand, enforced with computer algebra systems). The direct connections with the theory of phase transitions, algebra of non-commutative operators and decorated spin models will be elucidated.
Keywords:Biophysics, protein folding, helix-coil transition, spin models
Place of performance:Institut za fiziku, Bijenička 46, 10000 Zagreb, Hrvaska
Year of performance:2016
PID:20.500.12556/RUNG-2852-7efcdcc2-a2c8-a81f-b68a-151f43b8e5c2 New window
COBISS.SI-ID:4603899 New window
NUK URN:URN:SI:UNG:REP:MXBVMU6Y
Publication date in RUNG:13.12.2016
Views:6145
Downloads:0
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