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Title:Molecules involved in motility regulation in Escherichia coli cells: a review
Authors:Khan, Fazlurrahman (Author)
Tabassum, Nazia (Author)
:Pham, Dung (Author)
Oloketuyi, Sandra (Author)
Kim, Young-Mog (Author)
Files:This document has no files. This document may have a phisical copy in the library of the organization, check the status via COBISS. Link is opened in a new window
Language:English
Work type:Not categorized (r6)
Tipology:1.01 - Original Scientific Article
Organization:UNG - University of Nova Gorica
Abstract:The initial colonization of the host organism by commensal, probiotic, and pathogenic Escherichia coli strains is an important step in the development of infections and biofilms. Sensing and colonization of host cell surfaces are governed by flagellar and fimbriae/pili appendages, respectively. Biofilm formation confers great advantages on pathogenic E. coli cells such as protection against the host immune system, antimicrobial agents, and several environmental stress factors. The transition from planktonic to sessile physiological states involves several signaling cascades and factors responsible for the regulation of flagellar motility in E. coli cells. These regulatory factors have thus become important targets to control pathogenicity. Hence, attenuation of flagellar motility is considered a potential therapy against pathogenic E. coli. The present review describes signaling pathways and proteins involved in direct or indirect regulation of flagellar motility. Furthermore, application strategies for antimotility natural or synthetic compounds are discussed also.
Keywords:Biofilm formation, Escherichia coli, inhibition, motility, pathogenesis
Year of publishing:2020
Number of pages:1-20
Numbering:36, 8
COBISS_ID:47104003 Link is opened in a new window
URN:URN:SI:UNG:REP:FXPUJ0U7
DOI:10.1080/08927014.2020.1826939 Link is opened in a new window
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Title:Biofouling
Year of publishing:2020

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