Repository of University of Nova Gorica

Show document
A+ | A- | Help | SLO | ENG

Title:Biological applications of porous polymers and covalent organic frameworks : lecture at the Otto-von-Guericke Universität Magdeburg, Tuesday, 27th June 2023, Magdeburg, Germany
Authors:ID Škorjanc, Tina (Author)
Files: This document has no files that are freely available to the public. This document may have a physical copy in the library of the organization, check the status via COBISS. Link is opened in a new window
Language:English
Work type:Unknown
Typology:3.15 - Unpublished Conference Contribution
Organization:UNG - University of Nova Gorica
Abstract:Porous organic polymers (POPs) and covalent organic frameworks (COFs) have gained significant attention in the scientific community for a wide array of applications because of their attractive physical and chemical properties. Porosity of these materials provides ample surface area for interaction with targets, while crystallinity allows for highly specific structural tuning. In this seminar, I will present two strategies of utilizing these features of newly prepared materials in biosensing. Firstly, a cationic POP was synthesized, deposited onto interdigitated electrode arrays via a nontraditional electrophoresis technique, and utilized for electrochemical sensing of bacterial cells. As the principle of detection relied on electrostatic interactions between the cationic POP and the anionic bacterial surface, the sensor operated for both Gram-positive and Gram-negative bacteria. Secondly, a small-molecule nitroimidazole target for hypoxia, a low oxygen environment present in tumors, was post-synthetically conjugated to the pores of a fluorescent COF. This material served as a useful hypoxia imaging agent in cancerous cells. The seminar will conclude with some future perspectives on POPs and COFs in biological applications followed by Q & A.
Keywords:Porous organic polymers, covalent organic frameworks, biosensors, hypoxia
Year of publishing:2023
PID:20.500.12556/RUNG-8295-b5816de2-e23c-6eb1-d503-46b864b7f0bf New window
COBISS.SI-ID:158691843 New window
UDC:54
NUK URN:URN:SI:UNG:REP:WJB13GDI
Publication date in RUNG:13.07.2023
Views:1080
Downloads:0
Metadata:XML RDF-CHPDL DC-XML DC-RDF
:
Copy citation
  
Average score:(0 votes)
Your score:Voting is allowed only for logged in users.
Share:Bookmark and Share


Hover the mouse pointer over a document title to show the abstract or click on the title to get all document metadata.

Record is a part of a monograph

Title:Otto-von-Guericke Universität Magdeburg
Place of publishing:Magdeburg
Year of publishing:2023

Document is financed by a project

Funder:EC - European Commission
Funding programme:H2020
Project number:101038091
Name:Novel COF-based sensors for detecting organic agents in water
Acronym:COFsensor

Back