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Title:Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations
Authors:ID Bai, Zixuan (Author)
ID Wang, Jiewen (Author)
ID Liu, Jiaqi (Author)
ID Yuan, Haibin (Author)
ID Wang, Ping (Author)
ID Zhang, Miao (Author)
ID Feng, Yuanhang (Author)
ID Cao, Xiangtong (Author)
ID Cao, Xiangan (Author)
ID Kang, Guangbo (Author)
ID De Marco, Ario (Author)
ID Huang, He (Author)
Files:.pdf Bispecific_Nb.pdf (8,75 MB)
MD5: 1AD683046992927D8EC1D6F90C040C63
 
URL https://www.sciencedirect.com/science/article/pii/S2001037022005785?via%3Dihub
 
Language:English
Work type:Unknown
Typology:1.01 - Original Scientific Article
Organization:UNG - University of Nova Gorica
Keywords:nanobody rational design, bispecific binders, protein activity inhibition
Publication date:01.01.2023
Year of publishing:2023
Number of pages:str. 601-613
Numbering:21, Vol. 21
PID:20.500.12556/RUNG-7821-96462a96-083d-dc04-f93e-26a0443b307d New window
COBISS.SI-ID:135868419 New window
UDC:577
ISSN on article:2001-0370
DOI:10.1016/j.csbj.2022.12.021 New window
NUK URN:URN:SI:UNG:REP:1F2XQNGT
Publication date in RUNG:03.01.2023
Views:1558
Downloads:3
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Record is a part of a journal

Title:Computational and Structural Biotechnology Journal
Publisher:Chalmers University of Technology
ISSN:2001-0370
COBISS.SI-ID:5068826 New window

Licences

License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Link:http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:02.01.2023

Secondary language

Language:Slovenian
Keywords:viskoznost, proteinske formulacije, biofarmacevtski izdelki, sredstva za zmanjševanje viskoznosti, računalniško preverjanje


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