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Title:Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations
Authors:ID Bai, Zixuan, Tianjin University (Author)
ID Wang, Jiewen, Tianjin University (Author)
ID Li, Jiaqi, Tianjin University (Author)
ID Yuan, Haibin, Tianjin University (Author)
ID Wang, Ping, TCMT Tianjin (Author)
ID Zhang, Miao, CRBC Beijing (Author)
ID Feng, Yuanhang, Tianjin University (Author)
ID Cao, Xiangtong, Tianjin University (Author)
ID Cao, Xiangan, Tianjin University (Author)
ID Kang, Guangbo, Tianjin University (Author)
ID de Marco, Ario, University of Nova Gorica (Author)
ID Huang, He, Tianjin University (Author)
Files:This document has no files that are freely available to the public. This document may have a physical copy in the library of the organization, check the status via COBISS. Link is opened in a new window
Work type:Not categorized
Typology:1.01 - Original Scientific Article
Organization:UNG - University of Nova Gorica
Keywords:nanobody rational design, bispecific binders, protein activity inhibition
Year of publishing:2023
Number of pages:601-613
PID:20.500.12556/RUNG-7821 New window
COBISS.SI-ID:135868419 New window
Publication date in RUNG:03.01.2023
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Record is a part of a journal

Title:Computational and Structural Biotechnology Journal
Year of publishing:2023


License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:02.01.2023